| Pharmaceutical Information |
| Drug Name |
Viloxazine |
| Drug ID |
BADD_D02607 |
| Description |
Viloxazine is a selective norepinephrine reuptake inhibitor (NRI) that was used in some European countries as an antidepressant drug. It structurally differs from conventional tri- or tetra-cyclic antidepressants and it does not produce sedative anticholinergic or adrenergic effects in man [A19781]. While displaying amphetamine-like CNS stimulant effects, there is little evidence of drug dependence from viloxazine therapy. Viloxazine hydrochloride is a common active ingredient in drug formulation. It was discovered and brought to market in 1976 by Imperial Chemical Industries and in early 2000's, it was withdrawn from the market. |
| Indications and Usage |
Indicated for the treatment of clinical depression. |
| Marketing Status |
approved; investigational; withdrawn |
| ATC Code |
N06AX09 |
| DrugBank ID |
DB09185
|
| KEGG ID |
D08673
|
| MeSH ID |
D014745
|
| PubChem ID |
5666
|
| TTD Drug ID |
D0V9JR
|
| NDC Product Code |
70600-039 |
| UNII |
5I5Y2789ZF
|
| Synonyms |
Viloxazine | ICI-58,834 | ICI58,834 | Viloxazine Hydrochloride | Viloxazine Hydrochloride, (R)-Isomer | Vivalan | Viloxazine Oxalate (1:1) | Viloxazine, (+-)-Isomer | Viloxazine, (R)-Isomer | Viloxazine, (S)-Isomer | Emovit | Viloxazine Hydrochloride, (S)-Isomer |
|
| Chemical Information |
| Molecular Formula |
C13H19NO3 |
| CAS Registry Number |
46817-91-8 |
| SMILES |
CCOC1=CC=CC=C1OCC2CNCCO2 |
| Chemical Structure |
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| ADRs Induced by Drug |
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