Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Calcium carbonate
Drug ID BADD_D02616
Description Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ions and prostaglandins may also confer cytoprotective effects. Calcium carbonate may also be used as a nutritional supplement or to treat hypocalcemia.
Indications and Usage For relief of heartburn and acid indigestion. May also be used as a nutritional supplement or to treat hypocalcemia.
Marketing Status approved; investigational
ATC Code A02AC01; A12AA04
DrugBank ID DB06724
KEGG ID D00932; D10802
MeSH ID D002119
PubChem ID 10112
TTD Drug ID Not Available
NDC Product Code 73408-921; 0924-0287; 53004-0540; 53004-0560; 68210-4188; 11822-1156; 21130-184; 24385-485; 36800-828; 37000-446; 37808-103; 0135-0118; 37808-494; 0135-0180; 0135-0569; 41163-881; 0135-0630; 41250-965; 49314-1023; 50804-012; 53041-130; 54738-030; 55910-590; 57896-763; 62011-0229; 0363-2730; 63868-049; 63868-703; 63941-010; 63941-021; 67091-226; 67091-356; 67091-365; 68163-102; 68599-1411; 69168-219; 69626-0008; 69842-060; 70518-2265; 76162-130; 79481-0041; 82431-102; 82431-104; 82585-303; 11737-200; 12784-440; 67054-003; 11673-040; 11822-0048; 11822-1039; 11822-1512; 21130-310; 21130-515; 21130-971; 30142-307; 36800-468; 36800-595; 37808-464; 0135-0245; 37835-115; 41250-135; 0135-0642; 0135-1001; 41250-669; 41250-723; 41415-103; 41520-468; 41520-485; 42681-0028; 42681-0029; 47682-089; 47682-820; 47682-920; 49035-048; 49035-778; 49348-055; 50594-028; 55910-070; 0280-0002; 0280-0059; 63868-048; 63868-122; 63868-700; 68016-700; 68163-011; 68391-102; 69103-2552; 69676-0060; 69842-396; 69842-440; 71481-010; 71481-011; 72476-026; 73659-015; 76162-127; 82932-402; 82932-801; 53004-0660; 65376-0410; 11673-060; 21130-136; 21130-302; 21130-913; 27854-120; 30142-036; 30142-200; 36800-203; 36800-489; 36800-830; 37808-101; 37808-137; 0135-0154; 0135-0181; 0135-0183; 37835-184; 0135-0633; 41250-363; 0135-1002; 0135-1328; 41250-691; 41520-035; 41520-905; 50804-127; 51316-051; 51316-052; 55301-202; 55910-077; 55910-089; 55910-692; 0280-0042; 0280-0245; 62211-239; 63868-161; 63868-701; 63868-702; 67091-330; 69676-0043; 69790-089; 69842-015; 69842-362; 69842-363; 70000-0430; 70000-0431; 70369-005; 70677-1081; 71481-007; 55301-595; 55910-605; 0280-0221; 62011-0482; 62211-196; 67091-224; 67091-359; 68998-102; 69790-820; 69842-360; 70369-004; 70677-0067; 70677-1076; 71481-002; 71481-003; 76162-131; 79481-0042; 79903-103; 79903-200; 82431-105; 82932-602; 82932-701; 53004-0440; 53004-0460; 53004-0480; 53004-0490; 53004-0580; 66218-100; 67054-004; 11673-715; 11822-1029; 21130-130; 21130-501; 30142-039; 30142-162; 36800-485; 37808-132; 0135-0074; 0135-0178; 0135-0540; 41250-108; 41250-392; 0135-1000; 41415-102; 47682-088; 49314-1013; 53041-098; 0363-1083; 0363-9201; 63868-127; 67091-227; 69842-271; 69842-368; 71481-000; 71481-004; 71481-009; 71481-012; 71481-013; 71481-014; 80733-005; 82431-103; 55570-130; 65376-0412; 11673-051; 11673-156; 11788-021; 11822-0216; 11822-0596; 30142-038; 0121-4766; 0135-0076; 0135-0155; 0135-0553; 0135-0612; 41250-270; 41250-553; 0135-1326; 41415-101; 47682-092; 49035-167; 50804-113; 50804-171; 50804-175; 55670-141; 59779-596; 0363-1082; 0363-1093; 63868-057; 63941-022; 68998-101; 69168-229; 69842-184; 70000-0034; 70000-0592; 0536-1225; 0536-1229; 70677-1079; 71481-005; 82932-401; 58103-134; 62211-241; 65376-0413; 65376-3630; 17714-041; 30142-108; 30142-300; 36800-478; 36800-881; 36800-962; 0135-0456; 0135-0560; 0135-0610; 41250-109; 41250-298; 41250-566; 41415-201; 41520-031; 49035-803; 51316-050; 51376-127; 52642-035; 53041-127; 55301-102; 55301-203; 62011-0398; 0363-1081; 0363-5960; 63868-035; 0363-9952; 67091-358; 69103-2516; 70677-1075; 71481-008; 71713-204; 73598-1142; 76162-129; 80733-007; 82431-101; 82932-501; 0924-0086; 53004-0510; 58103-132; 58103-136; 65376-0414; 11822-0312; 21130-138; 21130-201; 24385-106; 30142-204; 0121-0766; 37808-063; 37808-135; 0135-0071; 0135-0228
UNII H0G9379FGK
Synonyms Calcium Carbonate | Carbonate, Calcium | Aragonite | Vaterite | Calcite | Limestone | Marble | Milk of Calcium | Calcium Milk | Chalk
Chemical Information
Molecular Formula CaCO3
CAS Registry Number 471-34-1
SMILES C(=O)([O-])[O-].[Ca+2]
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal discomfort07.01.06.001--Not Available
Abdominal pain07.01.05.002--
Back pain15.03.04.005--
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Choking22.12.03.003--Not Available
Colitis ulcerative10.02.01.004; 07.08.01.005--Not Available
Condition aggravated08.01.03.004--Not Available
Diarrhoea07.02.01.001--
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Dyspnoea02.11.05.003; 22.02.01.004--
Fatigue08.01.01.002--
Headache17.14.01.001--
Myalgia15.05.02.001--
Nausea07.01.07.001--
Nephrolithiasis20.04.01.002--
Pain08.01.08.004--
Palpitations02.11.04.012--
Paraesthesia23.03.03.094; 17.02.06.005--
Pyrexia08.05.02.003--
Rash pruritic23.03.13.030--Not Available
Stomatitis07.05.06.005--
Therapeutic response unexpected08.06.01.001--Not Available
Urticaria10.01.06.001; 23.04.02.001--
Vomiting07.01.07.003--
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