Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Methoxyflurane
Drug ID BADD_D02626
Description An inhalation anesthetic. Currently, methoxyflurane is rarely used for surgical, obstetric, or dental anesthesia. If so employed, it should be administered with nitrous oxide to achieve a relatively light level of anesthesia, and a neuromuscular blocking agent given concurrently to obtain the desired degree of muscular relaxation. (From AMA Drug Evaluations Annual, 1994, p180)
Indications and Usage For use in the induction and maintenance of general anesthesia
Marketing Status approved; investigational; vet_approved
ATC Code N02BG09
DrugBank ID DB01028
KEGG ID D00544
MeSH ID D008733
PubChem ID 4116
TTD Drug ID D07SOO
NDC Product Code Not Available
UNII 30905R8O7B
Synonyms Methoxyflurane | Methofluranum | Penthrane | Pentrane | Anecotan
Chemical Information
Molecular Formula C3H4Cl2F2O
CAS Registry Number 76-38-0
SMILES COC(C(Cl)Cl)(F)F
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Dehydration14.05.05.001--
Diabetes insipidus14.05.07.003; 05.03.03.004--Not Available
Drug ineffective08.06.01.006--Not Available
Euphoric mood19.04.02.006--
Jaundice23.03.03.030; 09.01.01.004; 01.06.04.004--Not Available
Nausea07.01.07.001--
Nephrolithiasis20.04.01.002--
Polyuria20.02.03.002--Not Available
Pyrexia08.05.02.003--
Vomiting07.01.07.003--
Acute kidney injury20.01.03.016--
Inadequate analgesia12.02.20.006; 08.06.01.040--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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