Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Oxyphenbutazone
Drug ID BADD_D02630
Description Oxyphenbutazone was withdrawn from the Canadian market in March 1985 due to concerns regarding bone marrow suppression.
Indications and Usage Not Available
Marketing Status approved; withdrawn
ATC Code M01AA03; M02AA04; S01BC02
DrugBank ID DB03585
KEGG ID D08324
MeSH ID D010113
PubChem ID 4641
TTD Drug ID D06ZPS
NDC Product Code Not Available
UNII H806S4B3NS
Synonyms Oxyphenbutazone | Oxyphenylbutazone | Hydroxyphenylbutazone | Diflamil | Tanderil
Chemical Information
Molecular Formula C19H20N2O3
CAS Registry Number 129-20-4
SMILES CCCCC1C(=O)N(N(C1=O)C2=CC=C(C=C2)O)C3=CC=CC=C3
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Agranulocytosis01.02.03.001--Not Available
Asthenia08.01.01.001--Not Available
Dermatitis23.03.04.002--Not Available
Dyspnoea02.11.05.003; 22.02.01.004--
Epistaxis24.07.01.005; 22.04.03.001--
Erythema23.03.06.001--Not Available
Face oedema23.04.01.004; 10.01.05.002; 08.01.07.003--
Fluid retention20.01.02.003; 14.05.06.002--Not Available
Hepatitis09.01.07.004--Not Available
Hypersensitivity10.01.03.003--
Leukaemia16.01.03.001; 01.10.03.001--
Malaise08.01.01.003--
Oedema14.05.06.010; 08.01.07.006--Not Available
Pruritus23.03.12.001--
Purpura01.01.04.003; 24.07.06.005; 23.06.01.004--
Pyrexia08.05.02.003--
Rash23.03.13.001--Not Available
Rash maculo-papular23.03.13.004--
Rash papular23.03.13.017--Not Available
Serum sickness12.02.08.004; 10.01.03.004--
Stevens-Johnson syndrome10.01.01.045; 23.03.01.007; 12.03.01.014; 11.07.01.005--
Stomatitis07.05.06.005--
Thrombocytopenia01.08.01.002--Not Available
Urticaria23.04.02.001; 10.01.06.001--
Vomiting07.01.07.003--
Haemorrhage24.07.01.002--Not Available
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