Pharmaceutical Information |
Drug Name |
Terfenadine |
Drug ID |
BADD_D02637 |
Description |
In the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation. |
Indications and Usage |
For the treatment of allergic rhinitis, hay fever, and allergic skin disorders. |
Marketing Status |
approved; withdrawn |
ATC Code |
R06AX12 |
DrugBank ID |
DB00342
|
KEGG ID |
D00521
|
MeSH ID |
D016593
|
PubChem ID |
5405
|
TTD Drug ID |
D08SOF
|
NDC Product Code |
Not Available |
UNII |
7BA5G9Y06Q
|
Synonyms |
Terfenadine | Terfenidine | alpha-(4-(1,1-Dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-1-piperdinebutanol | Ternadin | Balkis Saft Spezial | Rapidal | RMI-9918 | RMI 9918 | RMI9918 | Seldane | Triludan | Teldane | Terfedura | Terfemundin | Terfenadin AL | Terfenadin Heumann | Terfenadin Stada | Terfenadin Von Ct | Terfenadin-Ratiopharm | Terfenadin Ratiopharm | Cyater | Hisfedin |
|
Chemical Information |
Molecular Formula |
C32H41NO2 |
CAS Registry Number |
50679-08-8 |
SMILES |
CC(C)(C)C1=CC=C(C=C1)C(CCCN2CCC(CC2)C(C3=CC=CC=C3)(C4=CC=CC=C4)O)O |
Chemical Structure |
|
|
ADRs Induced by Drug |
|
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
|
|