| Pharmaceutical Information |
| Drug Name |
Tryptophan |
| Drug ID |
BADD_D02639 |
| Description |
An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit inefficiently, in mammals. |
| Indications and Usage |
Tryptophan may be useful in increasing serotonin production, promoting healthy sleep, managing depression by enhancing mental and emotional well-being, managing pain tolerance, and managing weight. |
| Marketing Status |
approved; nutraceutical; withdrawn |
| ATC Code |
N06AX02 |
| DrugBank ID |
DB00150
|
| KEGG ID |
D00020
|
| MeSH ID |
D014364
|
| PubChem ID |
6305
|
| TTD Drug ID |
D05EJG
|
| NDC Product Code |
43742-0770 |
| UNII |
8DUH1N11BX
|
| Synonyms |
Tryptophan | L-Tryptophan | L Tryptophan | Levotryptophan | Ardeydorm | Ardeytropin | L-Tryptophan-ratiopharm | L Tryptophan ratiopharm | ratio-Tryptophan | ratio Tryptophan | Tryptophan Metabolism Alterations | PMS-Tryptophan | PMS Tryptophan | Trofan | Tryptacin | Tryptan | Optimax | Lyphan | Naturruhe |
|
| Chemical Information |
| Molecular Formula |
C11H12N2O2 |
| CAS Registry Number |
73-22-3 |
| SMILES |
C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)N |
| Chemical Structure |
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| ADRs Induced by Drug |
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*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
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| ADR Term |
ADReCS ID |
ADR Frequency (FAERS)
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
|
| Somnolence | 19.02.05.003; 17.02.04.006 | - | - | | | Tachycardia | 02.03.02.007 | - | - | Not Available | | Tremor | 17.01.06.002 | - | - | | | Vomiting | 07.01.07.003 | - | - | | | Withdrawal syndrome | 08.06.02.012; 19.07.06.023 | - | - | Not Available |
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