Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Apraxia
ADR ID BADD_A00319
ADR Hierarchy
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.03      Cortical dysfunction NEC
17.02.03.002      Apraxia
19      Psychiatric disorders
19.21      Cognitive and attention disorders and disturbances
19.21.01      Specific cognitive ability disturbances
19.21.01.002      Apraxia
Description A group of cognitive disorders characterized by the inability to perform previously learned skills that cannot be attributed to deficits of motor or sensory function. The two major subtypes of this condition are ideomotor (see APRAXIA, IDEOMOTOR) and ideational apraxia, which refers to loss of the ability to mentally formulate the processes involved with performing an action. For example, dressing apraxia may result from an inability to mentally formulate the act of placing clothes on the body. Apraxias are generally associated with lesions of the dominant PARIETAL LOBE and supramarginal gyrus. (From Adams et al., Principles of Neurology, 6th ed, pp56-7) [MeSH]
MedDRA Code 10003062
MeSH ID D001072; D020240
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Apraxia | Constructional apraxia | Dressing apraxia | Gaze apraxia | Ideational apraxia | Ideomotor apraxia | Apraxia of eyelid | Swallowing apraxia | Apraxias | Dyspraxia | Dyspraxias | Apraxia, Articulatory | Apraxias, Articulatory | Articulatory Apraxia | Articulatory Apraxias | Dyspraxia, Articulatory | Articulatory Dyspraxia | Articulatory Dyspraxias | Dyspraxias, Articulatory | Apraxia, Developmental Verbal | Apraxias, Developmental Verbal | Developmental Verbal Apraxia | Developmental Verbal Apraxias | Verbal Apraxia, Developmental | Verbal Apraxias, Developmental | Speech-Language Disorder 1 | 1s, Speech-Language Disorder | Disorder 1, Speech-Language | Disorder 1s, Speech-Language | Speech Language Disorder 1 | Speech-Language Disorder 1s | Developmental Verbal Dyspraxia | Developmental Verbal Dyspraxias | Dyspraxia, Developmental Verbal | Dyspraxias, Developmental Verbal | Verbal Dyspraxia, Developmental | Verbal Dyspraxias, Developmental | Apraxia, Facial-Oral | Apraxia, Facial Oral | Apraxias, Facial-Oral | Facial-Oral Apraxia | Facial-Oral Apraxias | Speech And Language Disorder With Orofacial Dyspraxia | Ideational Apraxia | Apraxia, Ideational | Apraxias, Ideational | Ideational Apraxias | Apraxia, Motor | Apraxias, Motor | Motor Apraxia | Motor Apraxias | Apraxia, Oral | Apraxias, Oral | Oral Apraxia | Oral Apraxias | Dyspraxia, Oral | Dyspraxias, Oral | Oral Dyspraxia | Oral Dyspraxias | Apraxia, Verbal | Apraxias, Verbal | Verbal Apraxia | Verbal Apraxias | Dyspraxia, Verbal | Dyspraxias, Verbal | Verbal Dyspraxia | Verbal Dyspraxias | Dressing Apraxia | Apraxia, Dressing | Apraxias, Dressing | Dressing Apraxias | Apraxia of Phonation | Phonation Apraxia | Phonation Apraxias | Apraxia, Gestural | Apraxias, Gestural | Gestural Apraxia | Gestural Apraxias
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00085Alprazolam0.000068%
BADD_D00165Aripiprazole0.000119%
BADD_D00312Bupropion0.000018%
BADD_D00356Carbamazepine0.000279%
BADD_D00499Clomipramine--
BADD_D00500Clomipramine hydrochloride--
BADD_D00511Clozapine0.002446%
BADD_D00563Dabigatran0.000856%
BADD_D00706Donepezil0.000106%
BADD_D00734Duloxetine0.000040%
BADD_D00981Gabapentin--
BADD_D00996Galantamine--
BADD_D00997Galantamine hydrobromide--
BADD_D01243Lamotrigine--
BADD_D01265Levetiracetam0.000238%
BADD_D01318Lorazepam0.000031%
BADD_D01378Memantine--
BADD_D01401Metformin0.000011%
BADD_D01449Metronidazole0.000026%
BADD_D01465Miglustat0.004312%
BADD_D01599Olanzapine0.000210%
BADD_D01633Oxaliplatin0.000224%
BADD_D01733Perampanel0.000125%
BADD_D01888Quetiapine0.000164%
BADD_D01951Risperidone0.000121%
BADD_D01956Rivastigmine tartrate--
BADD_D02002Selegiline--
BADD_D02003Selegiline hydrochloride--
BADD_D02104Tacrine hydrochloride--
BADD_D02247Topiramate0.000050%
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