Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Atrioventricular block first degree
ADR ID BADD_A00378
ADR Hierarchy
02      Cardiac disorders
02.03      Cardiac arrhythmias
02.03.01      Cardiac conduction disorders
02.03.01.004      Atrioventricular block first degree
Description A disorder characterized by a dysrhythmia with a delay in the time required for the conduction of an electrical impulse through the atrioventricular (AV) node beyond 0.2 seconds; prolongation of the PR interval greater than 200 milliseconds. [CTCAE]
MedDRA Code 10003674
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
1st degree heart block | Atrioventricular block first degree | Atrioventricular conduction time prolonged | AV block first degree | First degree atrioventricular block | Heart block 1st degree | Heart block AV first degree | Heart block first degree
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00983Gadobenate dimeglumine--
BADD_D00987Gadofosveset--
BADD_D00989Gadolinium--
BADD_D00996Galantamine--
BADD_D01132Idursulfase--
BADD_D01134Iloperidone--
BADD_D01136Imatinib--
BADD_D01194Irbesartan0.000505%
BADD_D01238Lacosamide0.003657%
BADD_D01300Lisinopril0.000005%
BADD_D01304Lithium cation0.000288%
BADD_D01322Losartan0.000010%
BADD_D01330Lurasidone--
BADD_D01331Lurasidone hydrochloride--
BADD_D01431Methylphenidate0.000041%
BADD_D01445Metoprolol0.000037%
BADD_D01447Metoprolol tartrate--
BADD_D01470Minocycline0.000177%
BADD_D01502Moxifloxacin hydrochloride--
BADD_D01512Nadolol--
BADD_D01567Nilotinib0.000280%
BADD_D01570Nisoldipine--
BADD_D01599Olanzapine0.000947%
BADD_D01621Optimark--
BADD_D01656Paliperidone--
BADD_D01657Paliperidone palmitate--
BADD_D01659Palonosetron--
BADD_D01765Phenytoin0.000287%
BADD_D01767Phosphonatoformate--
BADD_D01817Pramipexole--
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ADReCS-Target
ADR Term Drug Name Target