Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Autonomic nervous system imbalance
ADR ID BADD_A00402
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.010      Autonomic nervous system imbalance
17      Nervous system disorders
17.05      Neuromuscular disorders
17.05.01      Autonomic nervous system disorders
17.05.01.011      Autonomic nervous system imbalance
24      Vascular disorders
24.06      Decreased and nonspecific blood pressure disorders and shock
24.06.01      Blood pressure disorders NEC
24.06.01.005      Autonomic nervous system imbalance
Description Disorders of the AUTONOMIC NERVOUS SYSTEM occurring as a primary condition. Manifestations can involve any or all body systems but commonly affect the BLOOD PRESSURE and HEART RATE. [MeSH]
MedDRA Code 10003840
MeSH ID D054969
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Autonomic imbalance | Autonomic nervous system imbalance | Dysautonomia | Imbalance autonomic nervous system | Instability vasomotor | Autonomic instability | Autonomic dysfunction | Autonomic vascular dystonia | Psychovegetative syndrome | Vegetative dystonia | Neurovegetative neurosis | Neurocirculatory dystonia | Vasoneurosis | Vegetovascular dystonia | Vegetative neurosis | Vegetative nerve functional disturbance | Asthenic-vegetative syndrome | Angiodystonia | Primary Dysautonomias | Dysautonomia, Primary | Dysautonomias, Primary | Primary Dysautonomia | Dysautonomias
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01835Pregabalin0.000166%
BADD_D01848Prochlorperazine--
BADD_D01888Quetiapine0.000055%
BADD_D01916Rasagiline mesylate--
BADD_D01951Risperidone0.000121%
BADD_D02010Sertraline0.000034%
BADD_D02047Sodium oxybate0.001583%
BADD_D02056Somatuline depot--
BADD_D02107Tafamidis0.000808%
BADD_D02175Tetrabenazine--
BADD_D02200Thioridazine--
BADD_D02201Thioridazine hydrochloride--
BADD_D02230Tizanidine--
BADD_D02231Tizanidine hydrochloride--
BADD_D02236Tofacitinib0.001640%
BADD_D02261Tranexamic acid0.003117%
BADD_D02286Trimeprazine tartrate--
BADD_D02329Valproic acid0.000150%
BADD_D02355Vigabatrin0.000187%
BADD_D02389Ziprasidone hydrochloride--
BADD_D02392Zoledronic acid--
BADD_D02464Fingolimod0.000362%
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