Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01261Leuprolide monoacetate--
BADD_D01262Levalbuterol--
BADD_D01264Levalbuterol tartrate--
BADD_D01265Levetiracetam--
BADD_D01266Levobetaxolol hydrochloride--
BADD_D01269Levobupivacaine--
BADD_D01271Levocarnitine--
BADD_D01272Levocetirizine--
BADD_D01274Levodopa-4'-monophosphate--
BADD_D01275Levofloxacin--
BADD_D01279Levomepromazine maleate--
BADD_D01280Levomilnacipran hydrochloride--
BADD_D01281Levonorgestrel--
BADD_D01282Levorphanol-
BADD_D01283Levorphanol tartrate--
BADD_D01284Levosimendan--
BADD_D01285Levothyroxine0.000239%
BADD_D01292Linagliptin--
BADD_D01295Linezolid--
BADD_D01298Liraglutide--
BADD_D01299Lisdexamfetamine dimesylate--
BADD_D01300Lisinopril--
BADD_D01301Lisuride--
BADD_D01303Lithium carbonate0.001606%
BADD_D01306Lixisenatide--
BADD_D01309Lomefloxacin--
BADD_D01310Lomefloxacin hydrochloride--
BADD_D01311Lomitapide0.000786%
BADD_D01312Lomitapide mesylate--
BADD_D01314Loperamide cation--
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