Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01315Loperamide hydrochloride--
BADD_D01317Loratadine0.000135%
BADD_D01318Lorazepam--
BADD_D01319Lorcaserin hydrochloride--
BADD_D01320Lorcaserin hydrochloride hemihydrate--
BADD_D01321Lormetazepam--
BADD_D01322Losartan--
BADD_D01323Losartan potassium--
BADD_D01325Lovastatin--
BADD_D01326Loxapine--
BADD_D01327Loxapine succinate--
BADD_D01328Lubiprostone0.001363%
BADD_D01332Lutropin alfa--
BADD_D01341Magnesium citrate--
BADD_D01342Magnesium hydroxide0.017613%
BADD_D01343Magnesium sulfate--
BADD_D01345Magnevist--
BADD_D01350Maprotiline--
BADD_D01351Maprotiline hydrochloride--
BADD_D01352Maraviroc--
BADD_D01356Mecamylamine--
BADD_D01357Mecamylamine hydrochloride--
BADD_D01363Meclofenamate sodium--
BADD_D01366Medroxyprogesterone acetate--
BADD_D01368Mefenamic acid--
BADD_D01371Megestrol--
BADD_D01372Megestrol acetate--
BADD_D01373Melatonin0.000907%
BADD_D01374Meloxicam--
BADD_D01375Meloxicam sodium--
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