Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Constipation
ADR ID BADD_A01059
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.02      Gastrointestinal atonic and hypomotility disorders NEC
07.02.02.001      Constipation
Description A disorder characterized by irregular and infrequent or difficult evacuation of the bowels. [CTCAE] Infrequent or difficult evacuation of FECES. These symptoms are associated with a variety of causes, including low DIETARY FIBER intake, emotional or nervous disturbances, systemic and structural disorders, drug-induced aggravation, and infections. | Difficult defecation. | Symptom characterized by the passage of stool once a week or less. [MeSH]
MedDRA Code 10010774
MeSH ID D003248
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Constipation | Constipation (excl faecal impaction) | Iatrogenic constipation | Obstipation | Constipation aggravated | Constipation (excl fecal impaction) | Stools absent | Constipation chronic | Opioid induced constipation | Slow transit constipation | Chronic idiopathic constipation | Absent bowel movement | Habitual constipation | Dyschezia | Colonic Inertia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00347Candesartan cilexetil--
BADD_D00349Capecitabine0.009324%
BADD_D00354Captopril--
BADD_D00356Carbamazepine--
BADD_D00359Carbidopa--
BADD_D00361Carbinoxamine--
BADD_D00362Carbinoxamine maleate--
BADD_D00364Carboplatin--
BADD_D00367Carfilzomib--
BADD_D00368Carglumic acid0.013800%
BADD_D00369Cariprazine--
BADD_D00371Carmustine--
BADD_D00374Carvedilol--
BADD_D00376Caspofungin--
BADD_D00377Caspofungin acetate--
BADD_D00378Cefaclor--
BADD_D00384Cefdinir--
BADD_D00385Cefditoren pivoxil--
BADD_D00386Cefepime--
BADD_D00395Cefpodoxime--
BADD_D00398Ceftaroline fosamil--
BADD_D00401Ceftibuten dihydrate--
BADD_D00404Ceftobiprole--
BADD_D00410Celecoxib--
BADD_D00414Ceritinib0.001019%
BADD_D00415Cerivastatin--
BADD_D00417Cetirizine--
BADD_D00418Cetirizine hydrochloride--
BADD_D00422Cetuximab--
BADD_D00424Cevimeline--
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