Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cough
ADR ID BADD_A01105
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.03      Coughing and associated symptoms
22.02.03.001      Cough
Description A disorder characterized by sudden, often repetitive, spasmodic contraction of the thoracic cavity, resulting in violent release of air from the lungs and usually accompanied by a distinctive sound. [CTCAE] A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs. [MeSH]
MedDRA Code 10011224
MeSH ID D003371
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cough | Cough increased | Cough nonproductive | Cough resembling asthma | Coughing | Dry cough | Irritant cough | Irritative cough | Nocturnal cough | Persistent dry cough | Persistent non-productive cough | Cough aggravated | Coughing after drug inhalation | Drug-induced cough | Smoker's cough | Paroxysmal cough | Acute cough | Chronic cough | Persistent cough | Painful cough | Cough ineffective | Cough weak | Unexplained chronic cough | Refractory chronic cough | Coughs
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01191Ipratropium0.001432%
BADD_D01192Ipratropium bromide--
BADD_D01193Ipratropium bromide monohydrate--
BADD_D01194Irbesartan0.001615%
BADD_D01195Irinotecan--
BADD_D01196Irinotecan hydrochloride--
BADD_D01197Iron0.000453%
BADD_D01199Iron sucrose--
BADD_D01203Isoflurane--
BADD_D01204Isoniazid0.013899%
BADD_D01209Isosorbide--
BADD_D01211Isosorbide mononitrate--
BADD_D01216Isradipine--
BADD_D01217Itraconazole0.012025%
BADD_D01218Ivabradine0.001049%
BADD_D01220Ivacaftor-
BADD_D01221Ivermectin--
BADD_D01222Ixabepilone--
BADD_D01232Ketorolac0.000378%
BADD_D01233Ketorolac tromethamine--
BADD_D01240Lactulose0.000725%
BADD_D01241Lamisil--
BADD_D01242Lamivudine--
BADD_D01243Lamotrigine--
BADD_D01245Lansoprazole--
BADD_D01247Lanthanum carbonate0.001239%
BADD_D01248Lapatinib--
BADD_D01250Lasofoxifene--
BADD_D01251Latanoprost0.000891%
BADD_D01252Leflunomide0.005356%
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ADReCS-Target
ADR Term Drug Name Target