Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cyanosis
ADR ID BADD_A01135
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.02      Respiratory disorders NEC
22.02.02      Conditions associated with abnormal gas exchange
22.02.02.007      Cyanosis
24      Vascular disorders
24.03      Vascular disorders NEC
24.03.01      Peripheral vascular disorders NEC
24.03.01.007      Cyanosis
02      Cardiac disorders
02.11      Cardiac disorders, signs and symptoms NEC
02.11.04      Cardiac signs and symptoms NEC
02.11.04.004      Cyanosis
23      Skin and subcutaneous tissue disorders
23.06      Skin vascular abnormalities
23.06.04      Skin vascular conditions NEC
23.06.04.005      Cyanosis
Description A disorder characterized by a bluish discoloration of the skin and/or mucous membranes. [CTCAE] A bluish or purplish discoloration of the skin and mucous membranes due to an increase in the amount of deoxygenated hemoglobin in the blood or a structural defect in the hemoglobin molecule. [MeSH]
MedDRA Code 10011703
MeSH ID D003490
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE)
Synonym
Acrocyanosis | Blue lips | Cyanosed | Cyanosis | Cyanosis NOS | Cyanosis of lip | Cyanosis peripheral | Cyanotic | Lips cyanosed | Nails cyanosed | Circumoral cyanosis | Cyanosis aggravated | Blue skin | Cyanoses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02079Succinylcholine--
BADD_D02082Sufentanil0.000179%
BADD_D02084Sugammadex0.001859%
BADD_D02093Sulfasalazine--
BADD_D02098Sumatriptan0.000056%
BADD_D02099Sumatriptan succinate--
BADD_D02106Tadalafil0.000625%
BADD_D02153Teniposide--
BADD_D02167Terlipressin--
BADD_D02192Thalidomide--
BADD_D02195Theophylline--
BADD_D02197Thiamine--
BADD_D02198Thiamine hydrochloride--
BADD_D02254Tramadol0.000051%
BADD_D02268Treprostinil0.000510%
BADD_D02270Tretinoin--
BADD_D02303Tropicamide0.002402%
BADD_D02320Urokinase--
BADD_D02329Valproic acid0.000649%
BADD_D02346Venlafaxine--
BADD_D02348Verapamil0.000148%
BADD_D02355Vigabatrin0.000585%
BADD_D02369Voriconazole--
BADD_D02373Warfarin--
BADD_D02375Water--
BADD_D02378Zalcitabine--
BADD_D02379Zaleplon--
BADD_D02393Zolmitriptan--
BADD_D02412Octreotide0.000186%
BADD_D02416Ropivacaine0.000179%
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