Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Terlipressin
Drug ID BADD_D02167
Description Terlipressin is an analogue of vasopressin used as a vasoactive drug in the management of hypotension which has been found to be effective when norepinephrine fails.
Indications and Usage Commonly used to stop bleeding of varices in the food pipe (oesophagus).
Marketing Status approved; investigational
ATC Code H01BA04
DrugBank ID DB02638
KEGG ID D06672
MeSH ID D000077585
PubChem ID 72081
TTD Drug ID D0P4VX
NDC Product Code 41701-009; 41701-016; 43825-200
UNII 7Z5X49W53P
Synonyms Terlipressin | Glycylpressin | TGLVP | Terlypressin | Triglycyl Lysine Vasopressin | Triglycylvasopressin | Glipressin | Glypressin | Triglycyl-(8-lysine)vasopressin | Gly-Gly-Gly-8-Lys-vasopressin | Gly Gly Gly 8 Lys vasopressin | N-(alpha)-glycyl-glycyl-glycyl-8-lysine vasopressin | Vasopressin, tri-Gly-8-Lys- | tri-Gly-8-Lys- Vasopressin | Remestyp
Chemical Information
Molecular Formula C52H74N16O15S2
CAS Registry Number 14636-12-5
SMILES C1CC(N(C1)C(=O)C2CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N) CC3=CC=CC=C3)CC4=CC=C(C=C4)O)NC(=O)CNC(=O)CNC(=O)CN)C(=O)NC(CCCCN)C(=O)NCC(=O)N
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Atrial fibrillation02.03.03.002--
Blood creatinine decreased13.13.01.003--Not Available
Bradycardia02.03.02.002--Not Available
Cardiac failure02.05.01.001--
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Cyanosis02.11.04.004; 24.03.01.007; 22.02.02.007; 23.06.04.005--
Diarrhoea07.02.01.001--
Dyspnoea02.11.05.003; 22.02.01.004--
Gastrointestinal disorder07.11.01.001--Not Available
Headache17.14.01.001--
Hypertension24.08.02.001--
Hypervolaemia02.05.04.019; 14.05.06.003--Not Available
Hyponatraemia14.05.04.002--
Injection site necrosis12.07.03.020; 08.02.03.020--Not Available
Intestinal ischaemia24.04.08.001; 07.15.02.001--Not Available
Menopausal symptoms21.02.02.002--Not Available
Mesenteric vascular insufficiency24.04.08.011; 07.15.02.010--Not Available
Myocardial infarction24.04.04.009; 02.02.02.007--
Nausea07.01.07.001--
Nervous system disorder17.02.10.001--Not Available
Pallor24.03.04.001; 23.03.03.031; 08.01.03.032--Not Available
Peripheral ischaemia24.04.03.002--
Pregnancy18.08.02.004--Not Available
Pulmonary oedema02.05.02.003; 22.01.03.003--
Respiratory distress22.02.01.012--Not Available
Respiratory failure22.02.06.002; 14.01.04.003--
Skin disorder23.03.03.007--Not Available
Skin exfoliation23.03.07.003--Not Available
Skin necrosis23.03.03.011--Not Available
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