Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Demyelinating disorders
ADR ID BADD_A01193
ADR Hierarchy
17      Nervous system disorders
17.16      Demyelinating disorders
Description Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system. | The first region-restricted episode of CNS inflammatory demyelination in a patient. It is usually characterized by an acute monosymptomatic presentation of the optic nerves, brainstem, or spinal cord. It may not reoccur (isolated), or it may progress to MULTIPLE SCLEROSIS. [MeSH]
MedDRA Code 10012303
MeSH ID D003711
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Demyelinating Diseases | Demyelinating Disease | Demyelinating Disorders | Demyelinating Disorder | Demyelination | Demyelinations | Clinically Isolated Syndrome, CNS Demyelinating | Clinically Isolated CNS Demyelinating Syndrome
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00023Acetaminophen--
BADD_D00033Acetylsalicylic acid0.000022%
BADD_D00039Acyclovir0.000071%
BADD_D00041Adalimumab--
BADD_D00062Aldesleukin--
BADD_D00064Alemtuzumab--
BADD_D00066Alendronic acid0.000110%
BADD_D00097Amantadine--
BADD_D00118Amitriptyline--
BADD_D00129Amoxicillin0.000012%
BADD_D00171Ascorbic acid--
BADD_D00195Azathioprine0.001253%
BADD_D00209Baclofen0.001198%
BADD_D00223Belatacept--
BADD_D00260Betamethasone--
BADD_D00284Bortezomib--
BADD_D00291Brentuximab vedotin--
BADD_D00306Budesonide--
BADD_D00344Canagliflozin--
BADD_D00356Carbamazepine0.000186%
BADD_D00364Carboplatin0.000280%
BADD_D00417Cetirizine--
BADD_D00424Cevimeline--
BADD_D00425Cevimeline hydrochloride--
BADD_D00475Citalopram--
BADD_D00479Cladribine0.019416%
BADD_D00490Clobetasol propionate0.003735%
BADD_D00511Clozapine0.001223%
BADD_D00526Conivaptan--
BADD_D00549Cyclophosphamide--
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