Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Demyelinating disorders
ADR ID BADD_A01193
ADR Hierarchy
17      Nervous system disorders
17.16      Demyelinating disorders
Description Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system. | The first region-restricted episode of CNS inflammatory demyelination in a patient. It is usually characterized by an acute monosymptomatic presentation of the optic nerves, brainstem, or spinal cord. It may not reoccur (isolated), or it may progress to MULTIPLE SCLEROSIS. [MeSH]
MedDRA Code 10012303
MeSH ID D003711
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Demyelinating Diseases | Demyelinating Disease | Demyelinating Disorders | Demyelinating Disorder | Demyelination | Demyelinations | Clinically Isolated Syndrome, CNS Demyelinating | Clinically Isolated CNS Demyelinating Syndrome
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00551Cyclosporine0.000166%
BADD_D00574Dalfampridine0.106539%
BADD_D00586Darunavir--
BADD_D00616Desmopressin0.001283%
BADD_D00620Desoximetasone--
BADD_D00623Dexamethasone0.000218%
BADD_D00668Digoxin0.000105%
BADD_D00680Dimethyl fumarate0.575546%
BADD_D00705Domperidone--
BADD_D00734Duloxetine0.000067%
BADD_D00768Enalaprilat0.002026%
BADD_D00775Enzalutamide0.000334%
BADD_D00794Ergocalciferol0.002394%
BADD_D00809Escitalopram0.000047%
BADD_D00838Etanercept--
BADD_D00844Ethinyl estradiol--
BADD_D00891Fesoterodine0.001985%
BADD_D00899Fingolimod hydrochloride--
BADD_D00914Fludarabine--
BADD_D00915Fludarabine phosphate--
BADD_D00931Fluorouracil--
BADD_D00952Folic acid--
BADD_D00981Gabapentin--
BADD_D00985Gadodiamide--
BADD_D00986Gadodiamide hydrate--
BADD_D01063Hepatitis b vaccine--
BADD_D01064Hepatitis b vaccine (recombinant)--
BADD_D01086Hydrocortisone0.000115%
BADD_D01103Hydroxychloroquine0.001859%
BADD_D01133Ifosfamide--
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