Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Diarrhoea
ADR ID BADD_A01261
ADR Hierarchy
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.01      Diarrhoea (excl infective)
07.02.01.001      Diarrhoea
Description An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight. [MeSH]
MedDRA Code 10012735
MeSH ID D003967
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Acute diarrhea | Antibiotic-associated diarrhea | Diarrhea | Diarrhea aggravated | Diarrhea NOS | Diarrhoea | Diarrhoea aggravated | Diarrhoea functional (due to spastic colon) | Diarrhoea NOS | Explosive diarrhoea | Frank diarrhoea | Functional diarrhea | Functional diarrhoea | Functional diarrhoea (due to spastic colon) | Iatrogenic diarrhea | Iatrogenic diarrhoea | Idiopathic diarrhea | Loose bowel | Loose bowels | Loose motions | Loose stools | Mushy stool | Nocturnal diarrhea | Secretory diarrhea | Stools loose | Stools watery | Urgent diarrhoea | Watery diarrhoea | Diarrhea functional (due to spastic colon) | Explosive diarrhea | Frank diarrhea | Functional diarrhea (due to spastic colon) | Urgent diarrhea | Watery diarrhea | Acute diarrhoea | Antibiotic-associated diarrhoea | Idiopathic diarrhoea | Nocturnal diarrhoea | Secretory diarrhoea | Mucous diarrhoea | Mucous diarrhea | Diarrhoea post chemotherapy | Diarrhea post chemotherapy | Osmotic diarrhea | Diarrhea recurrent | Diarrhoea recurrent | Chronic diarrhea | Chronic diarrhoea | Mushy diarrhoea | Mushy diarrhea | Malodorous diarrhea | Malodourous diarrhoea | Osmotic diarrhoea | Lienteric diarrhoea | Lienteric diarrhea | Diarrheas
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02393Zolmitriptan0.005213%
BADD_D02394Zolpidem--
BADD_D02395Zolpidem tartrate--
BADD_D02396Zonisamide--
BADD_D02397Zopiclone--
BADD_D02398Zuclopenthixol--
BADD_D02411Voxelotor-
BADD_D02412Octreotide0.014568%
BADD_D02415Ziprasidone--
BADD_D02428Loperamide0.003752%
BADD_D02432Glycopyrronium--
BADD_D02434Cinacalcet0.351818%
BADD_D02442Magnesium oxide0.001368%
BADD_D02453Midostaurin0.003503%
BADD_D02456Vilazodone0.028494%
BADD_D02462Methylnaltrexone0.004171%
BADD_D02467Naloxegol0.030911%
BADD_D02468Cannabidiol0.065963%
BADD_D02470Nintedanib0.061382%
BADD_D02471Oxygen--
BADD_D02472Sonidegib0.001175%
BADD_D02481Naldemedine0.005840%
BADD_D02483Ribociclib0.011114%
BADD_D02487Baricitinib--
BADD_D02489Neratinib0.068108%
BADD_D02490Apalutamide--
BADD_D02493Selinexor0.002026%
BADD_D02494Delafloxacin0.001157%
BADD_D02495Duvelisib0.003168%
BADD_D02498Abemaciclib0.093214%
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ADReCS-Target
ADR Term Drug Name Target