Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Dry eye
ADR ID BADD_A01343
ADR Hierarchy
06      Eye disorders
06.08      Eye disorders NEC
06.08.02      Lacrimation disorders
06.08.02.001      Dry eye
Description A disorder characterized by dryness of the cornea and conjunctiva. [CTCAE] Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur. [MeSH]
MedDRA Code 10013774
MeSH ID D015352; D007638
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Conjunctival xerosis | Dry eye | Dry eye NOS | Dry eye syndrome | Dry eyes | Dryness of eyes | Dryness under lids | Eye dryness | Eyes dry | Keratoconjunctivitis sicca | Keratoconjunctivitis sicca, not specified as Sjogren's | Dry eyes aggravated | Keratitis sicca | Corneal xerosis | Lacrimal gland insufficiency | Dry Eye Syndromes | Dry Eye Syndrome | Syndrome, Dry Eye | Syndromes, Dry Eye
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02316Unoprostone--
BADD_D02317Unoprostone isopropyl--
BADD_D02329Valproic acid--
BADD_D02334Vandetanib--
BADD_D02337Varenicline--
BADD_D02338Varenicline tartrate--
BADD_D02346Venlafaxine0.000103%
BADD_D02352Verteporfin--
BADD_D02353Vesicare--
BADD_D02356Vilazodone hydrochloride--
BADD_D02362Vinflunine--
BADD_D02369Voriconazole--
BADD_D02371Vortioxetine--
BADD_D02378Zalcitabine--
BADD_D02379Zaleplon--
BADD_D02389Ziprasidone hydrochloride--
BADD_D02391Ziprasidone mesylate--
BADD_D02393Zolmitriptan--
BADD_D02397Zopiclone--
BADD_D02407Upadacitinib--
BADD_D02412Octreotide--
BADD_D02432Glycopyrronium0.022507%
BADD_D02436Atorvastatin--
BADD_D02443Tiotropium0.000517%
BADD_D02445Solifenacin0.001736%
BADD_D02447Flavin mononucleotide-
BADD_D02456Vilazodone0.000703%
BADD_D02464Fingolimod0.010922%
BADD_D02483Ribociclib0.001063%
BADD_D02493Selinexor0.000381%
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