Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Dry eye
ADR ID BADD_A01343
ADR Hierarchy
06      Eye disorders
06.08      Eye disorders NEC
06.08.02      Lacrimation disorders
06.08.02.001      Dry eye
Description A disorder characterized by dryness of the cornea and conjunctiva. [CTCAE] Corneal and conjunctival dryness due to deficient tear production, predominantly in menopausal and post-menopausal women. Filamentary keratitis or erosion of the conjunctival and corneal epithelium may be caused by these disorders. Sensation of the presence of a foreign body in the eye and burning of the eyes may occur. [MeSH]
MedDRA Code 10013774
MeSH ID D015352; D007638
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Conjunctival xerosis | Dry eye | Dry eye NOS | Dry eye syndrome | Dry eyes | Dryness of eyes | Dryness under lids | Eye dryness | Eyes dry | Keratoconjunctivitis sicca | Keratoconjunctivitis sicca, not specified as Sjogren's | Dry eyes aggravated | Keratitis sicca | Corneal xerosis | Lacrimal gland insufficiency | Dry Eye Syndromes | Dry Eye Syndrome | Syndrome, Dry Eye | Syndromes, Dry Eye
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01786Pixantrone--
BADD_D01798Pomalidomide0.009572%
BADD_D01799Ponatinib--
BADD_D01804Posaconazole--
BADD_D01817Pramipexole--
BADD_D01818Pramipexole dihydrochloride--
BADD_D01832Prednisolone acetate0.015759%
BADD_D01835Pregabalin0.001120%
BADD_D01867Propranolol--
BADD_D01868Propranolol hydrochloride--
BADD_D01888Quetiapine--
BADD_D01889Quetiapine fumarate--
BADD_D01898Rabeprazole0.000703%
BADD_D01912Ranibizumab--
BADD_D01933Ribavirin0.039163%
BADD_D01934Riboflavin 5-phosphate--
BADD_D01946Rimexolone--
BADD_D01950Risedronic acid--
BADD_D01951Risperidone--
BADD_D01957Rizatriptan--
BADD_D01966Ropinirole--
BADD_D01971Rosuvastatin--
BADD_D01973Rotigotine0.000367%
BADD_D01989Saquinavir mesylate--
BADD_D01994Scopolamine0.000442%
BADD_D02002Selegiline--
BADD_D02006Selexipag0.000082%
BADD_D02016Sibutramine--
BADD_D02017Sibutramine hydrochloride--
BADD_D02018Sildenafil--
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