Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00702Dolasetron--
BADD_D00704Dolutegravir sodium0.007028%
BADD_D00706Donepezil--
BADD_D00707Donepezil hydrochloride--
BADD_D00712Dorzolamide--
BADD_D00713Dorzolamide hydrochloride--
BADD_D00714Dothiepin hydrochloride--
BADD_D00718Doxazosin--
BADD_D00719Doxazosin mesylate--
BADD_D00720Doxepin--
BADD_D00721Doxepin hydrochloride--
BADD_D00723Doxorubicin0.007443%
BADD_D00724Doxorubicin hydrochloride--
BADD_D00725Doxycycline0.000108%
BADD_D00729Dronabinol0.020793%
BADD_D00730Dronedarone0.008915%
BADD_D00732Droxidopa0.039767%
BADD_D00733Dulaglutide--
BADD_D00734Duloxetine0.039948%
BADD_D00735Duloxetine hydrochloride--
BADD_D00738Ecallantide--
BADD_D00742Eculizumab--
BADD_D00743Edetate calcium disodium--
BADD_D00745Edetic acid--
BADD_D00749Efavirenz--
BADD_D00754Elazop--
BADD_D00755Eletriptan--
BADD_D00757Eliglustat0.130234%
BADD_D00758Elosulfase alfa--
BADD_D00759Eltrombopag0.044697%
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ADReCS-Target
ADR Term Drug Name Target