Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00425Cevimeline hydrochloride--
BADD_D00429Chlorambucil--
BADD_D00444Chlorphenamine--
BADD_D00451Cholestyramine--
BADD_D00452Cholestyramine resin--
BADD_D00455Choline fenofibrate--
BADD_D00460Ciclesonide--
BADD_D00465Cilazapril monohydrate--
BADD_D00467Cimetidine--
BADD_D00469Cinacalcet hydrochloride--
BADD_D00471Ciprofloxacin0.000123%
BADD_D00475Citalopram--
BADD_D00476Citalopram hydrobromide--
BADD_D00479Cladribine0.006498%
BADD_D00480Clarithromycin--
BADD_D00481Clemastine fumarate--
BADD_D00483Clindamycin--
BADD_D00488Clobazam0.007814%
BADD_D00490Clobetasol propionate--
BADD_D00495Clofarabine--
BADD_D00496Clofazimine--
BADD_D00497Clomiphene--
BADD_D00498Clomiphene citrate--
BADD_D00499Clomipramine--
BADD_D00500Clomipramine hydrochloride--
BADD_D00501Clonazepam--
BADD_D00502Clonidine--
BADD_D00503Clonidine hydrochloride--
BADD_D00504Clopidogrel--
BADD_D00506Clorazepate dipotassium--
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ADReCS-Target
ADR Term Drug Name Target