Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Fatigue
ADR ID BADD_A01626
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.002      Fatigue
Description A disorder characterized by a state of generalized weakness with a pronounced inability to summon sufficient energy to accomplish daily activities. [CTCAE] The state of weariness following a period of exertion, mental or physical, characterized by a decreased capacity for work and reduced efficiency to respond to stimuli. [MeSH]
MedDRA Code 10016256
MeSH ID D005221
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Enervation | Exhaustion | Exhaustion due to excessive exertion | Exhaustion due to exposure | Fatigability | Fatigability generalized | Fatigability lumbar | Fatigability of knees | Fatigue | Fatigue extreme | Fatiguability | Lassitude | Loss physical strength | Prostration | TATT | Tired all the time | Tired and heavy | Tired out | Tiredness | Washed-out | Weariness | Worn out | Fatigue aggravated | Depressive weariness | Fatigueability generalised | Chronic fatigue | Fatiguability generalised
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00568Dacarbazine--
BADD_D00569Daclatasvir dihydrochloride--
BADD_D00571Dactinomycin--
BADD_D00574Dalfampridine0.094964%
BADD_D00576Danazol0.003541%
BADD_D00577Dantrolene sodium--
BADD_D00580Dapsone--
BADD_D00581Daptomycin--
BADD_D00582Daratumumab--
BADD_D00586Darunavir--
BADD_D00587Darunavir ethanolate--
BADD_D00588Dasabuvir--
BADD_D00589Dasatinib0.098586%
BADD_D00590Daunorubicin--
BADD_D00591Daunorubicin citrate--
BADD_D00593Decitabine--
BADD_D00594Deferasirox--
BADD_D00595Deferiprone0.012763%
BADD_D00599Degarelix--
BADD_D00600Degarelix acetate--
BADD_D00603Delavirdine--
BADD_D00604Delavirdine mesylate--
BADD_D00607Denileukin diftitox--
BADD_D00610Depreotide--
BADD_D00611Desflurane--
BADD_D00612Desipramine--
BADD_D00613Desipramine hydrochloride--
BADD_D00615Desloratadine--
BADD_D00616Desmopressin--
BADD_D00620Desoximetasone--
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ADReCS-Target
ADR Term Drug Name Target