Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Hepatotoxicity
ADR ID BADD_A02053
ADR Hierarchy
09      Hepatobiliary disorders
09.01      Hepatic and hepatobiliary disorders
09.01.07      Hepatocellular damage and hepatitis NEC
09.01.07.009      Hepatotoxicity
12      Injury, poisoning and procedural complications
12.03      Exposures, chemical injuries and poisoning
12.03.01      Poisoning and toxicity
12.03.01.008      Hepatotoxicity
Description Not Available
MedDRA Code 10019851
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Hepatotoxic effect | Hepatotoxicity | Hepatotoxicity aggravated | Hepatotoxicity NOS | Toxaemia of liver | Toxemia of liver | Toxic acute liver disease
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02453Midostaurin0.000168%
BADD_D02464Fingolimod--
BADD_D02470Nintedanib0.001645%
BADD_D02480Alectinib0.000358%
BADD_D02483Ribociclib0.001287%
BADD_D02490Apalutamide0.000667%
BADD_D02498Abemaciclib0.000336%
BADD_D02500Alpelisib0.000280%
BADD_D02504Lorlatinib0.000112%
BADD_D02505Gilteritinib0.000280%
BADD_D02509Brigatinib0.000112%
BADD_D02511Siponimod0.000362%
BADD_D02528Asciminib0.000112%
BADD_D02540Capmatinib0.000504%
BADD_D02548Darolutamide0.000334%
BADD_D02552Encorafenib--
BADD_D02588Remdesivir0.003218%
BADD_D02593Selpercatinib0.000302%
BADD_D02596Sotorasib0.001287%
BADD_D02603Tucatinib0.000112%
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ADReCS-Target
ADR Term Drug Name Target