Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Hiccups
ADR ID BADD_A02067
ADR Hierarchy
07      Gastrointestinal disorders
07.01      Gastrointestinal signs and symptoms
07.01.06      Gastrointestinal signs and symptoms NEC
07.01.06.009      Hiccups
22      Respiratory, thoracic and mediastinal disorders
22.12      Respiratory tract signs and symptoms
22.12.01      Lower respiratory tract signs and symptoms
22.12.01.001      Hiccups
Description A disorder characterized by repeated gulp sounds that result from an involuntary opening and closing of the glottis. This is attributed to a spasm of the diaphragm. [CTCAE] A spasm of the diaphragm that causes a sudden inhalation followed by rapid closure of the glottis which produces a sound. [MeSH]
MedDRA Code 10020039
MeSH ID D006606
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Hiccough | Hiccup | Hiccups | Singultation | Singultous | Singultus | Intractable hiccups | Persistent hiccups | Hiccoughs
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01564Nicotine0.002445%
BADD_D01565Nicotine alkaloid--
BADD_D01567Nilotinib0.000437%
BADD_D01598Ofloxacin--
BADD_D01599Olanzapine0.000631%
BADD_D01617Ondansetron--
BADD_D01618Ondansetron hydrochloride--
BADD_D01633Oxaliplatin0.000224%
BADD_D01637Oxcarbazepine--
BADD_D01643Oxybutynin--
BADD_D01645Oxycodone--
BADD_D01646Oxycodone hydrochloride--
BADD_D01653Paclitaxel0.000224%
BADD_D01654Palbociclib0.001310%
BADD_D01659Palonosetron--
BADD_D01660Palonosetron hydrochloride--
BADD_D01668Pantoprazole0.000041%
BADD_D01679Paroxetine--
BADD_D01680Paroxetine hydrochloride--
BADD_D01681Paroxetine hydrochloride hemihydrate--
BADD_D01682Paroxetine impurity a--
BADD_D01683Paroxetine mesylate--
BADD_D01687Pazopanib0.000168%
BADD_D01735Pergolide--
BADD_D01736Pergolide mesylate--
BADD_D01771Pilocarpine hydrochloride--
BADD_D01798Pomalidomide0.005401%
BADD_D01802Porfimer--
BADD_D01803Porfimer sodium--
BADD_D01804Posaconazole--
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