Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Hypertonia
ADR ID BADD_A02158
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.04      Muscle tone abnormalities
15.05.04.007      Hypertonia
17      Nervous system disorders
17.05      Neuromuscular disorders
17.05.02      Muscle tone abnormal
17.05.02.001      Hypertonia
Description Abnormal increase in skeletal or smooth muscle tone. Skeletal muscle hypertonicity may be associated with PYRAMIDAL TRACT lesions or BASAL GANGLIA DISEASES. [MeSH]
MedDRA Code 10020852
MeSH ID D009122
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Generally increased tone | Hypertonia | Hypertonicity | Hypertonus | Increased muscle tone | Muscular tone excessive | Muscular tone increased | Muscular tonus increased | Tone increased | Muscle hypertonia | Muscle Hypertonia | Hypertonia, Muscle | Hypertonias, Muscle | Muscle Hypertonias | Muscle Tone Increased | Increased, Muscle Tone | Tone Increased, Muscle | Muscular Hypertonicity | Hypertonicities, Muscular | Hypertonicity, Muscular | Muscular Hypertonicities | Hypermyotonia | Hypermyotonias | Hypertonia, Transient | Hypertonias, Transient | Transient Hypertonia | Transient Hypertonias | Hypertonia, Neonatal | Hypertonias, Neonatal | Neonatal Hypertonia | Neonatal Hypertonias | Hypertonia, Sphincter | Hypertonias, Sphincter | Sphincter Hypertonia | Sphincter Hypertonias | Hypertonia, Detrusor Muscle | Detrusor Muscle Hypertonia | Detrusor Muscle Hypertonias | Hypertonias, Detrusor Muscle | Muscle Hypertonia, Detrusor | Muscle Hypertonias, Detrusor | Hypertonia, Infantile | Hypertonias, Infantile | Infantile Hypertonia | Infantile Hypertonias
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01139Imipramine--
BADD_D01149Indapamide--
BADD_D01162Insulin detemir--
BADD_D01167Interferon alfa-2b--
BADD_D01169Interferon beta-1a--
BADD_D01170Interferon beta-1b--
BADD_D01178Iodixanol0.017783%
BADD_D01180Iohexol0.007113%
BADD_D01181Iopamidol--
BADD_D01182Iopromide--
BADD_D01185Iotrolan--
BADD_D01197Iron--
BADD_D01204Isoniazid0.002780%
BADD_D01213Isotretinoin--
BADD_D01243Lamotrigine0.000524%
BADD_D01245Lansoprazole--
BADD_D01261Leuprolide monoacetate--
BADD_D01262Levalbuterol--
BADD_D01263Levalbuterol hydrochloride--
BADD_D01266Levobetaxolol hydrochloride--
BADD_D01271Levocarnitine--
BADD_D01275Levofloxacin--
BADD_D01285Levothyroxine0.000005%
BADD_D01295Linezolid0.001647%
BADD_D01300Lisinopril--
BADD_D01303Lithium carbonate--
BADD_D01304Lithium cation0.000192%
BADD_D01305Lithium hydroxide--
BADD_D01309Lomefloxacin--
BADD_D01310Lomefloxacin hydrochloride--
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