Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Injection site reactions
ADR ID BADD_A02349
ADR Hierarchy
08      General disorders and administration site conditions
08.02      Administration site reactions
08.02.03      Injection site reactions
12      Injury, poisoning and procedural complications
12.07      Administration site reactions
12.07.03      Injection site reactions
Description Adverse reactions that occur initially at the site of injection or infusion. Milder type is confined to a local allergic flare reaction. A more severe reaction is caused by extravasation of VESICANTS from the blood vessel at the site of injection and can cause damage to the surrounding tissue. In tumor flare reaction symptoms involve well beyond the injection site such as an increase in the tumor size and tumor markers levels, bone pain, and HYPERCALCEMIA. [MeSH]
MedDRA Code 10022097
MeSH ID D000075662
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Injection Site Reaction | Injection Site Reactions | Injection Site Event | Injection Site Events | Injection Site Adverse Event | Infusion Site Reaction | Infusion Site Reactions | Infusion Site Adverse Reaction | Infusion Site Adverse Event
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02375Water1.134607%
BADD_D02389Ziprasidone hydrochloride--
BADD_D02391Ziprasidone mesylate--
BADD_D02392Zoledronic acid0.046093%
BADD_D02393Zolmitriptan0.003453%
BADD_D02394Zolpidem--
BADD_D02395Zolpidem tartrate--
BADD_D02397Zopiclone--
BADD_D02398Zuclopenthixol--
BADD_D02412Octreotide0.014698%
BADD_D02423Fondaparinux0.050820%
BADD_D02428Loperamide--
BADD_D02436Atorvastatin--
BADD_D02440Lisdexamfetamine0.000236%
BADD_D02445Solifenacin0.000174%
BADD_D02452Icatibant-
BADD_D02456Vilazodone0.001086%
BADD_D02462Methylnaltrexone0.001493%
BADD_D02464Fingolimod0.002532%
BADD_D02473Sodium chloride0.005600%
BADD_D02475Methylene blue0.000860%
BADD_D02498Abemaciclib--
BADD_D02536Bremelanotide0.000138%
BADD_D02537Cabotegravir0.001270%
BADD_D02539Calcium0.003249%
BADD_D02558Gadolinium cation (3+)-
BADD_D02568Lutetium oxodotreotide lu-177-
BADD_D02569Magnesium0.000647%
BADD_D02588Remdesivir0.009540%
BADD_D02611Aluminum hydroxide--
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ADReCS-Target
ADR Term Drug Name Target