Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Laryngospasm
ADR ID BADD_A02487
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.04      Upper respiratory tract disorders (excl infections)
22.04.02      Laryngeal spasm, oedema and obstruction
22.04.02.002      Laryngospasm
Description A disorder characterized by paroxysmal spasmodic muscular contraction of the vocal cords. [CTCAE] A disorder in which the adductor muscles of the VOCAL CORDS exhibit increased activity leading to laryngeal spasm. Laryngismus causes closure of the VOCAL FOLDS and airflow obstruction during inspiration. [MeSH]
MedDRA Code 10023891
MeSH ID D007826
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Glottic spasm | Laryngeal spasm | Laryngismus | Laryngospasm | Larynx muscle hypersensitive | Spasm glottis | Spasm larynx | Laryngospasms | Laryngeal Spasm | Laryngeal Spasms | Spasm, Laryngeal | Spasms, Laryngeal
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01707Penbutolol sulfate--
BADD_D01710Penicillin g--
BADD_D01712Penicillin g potassium--
BADD_D01714Penicillin g sodium--
BADD_D01717Pentamidine--
BADD_D01718Pentamidine isethionate--
BADD_D01743Perphenazine--
BADD_D01752Phenobarbital--
BADD_D01771Pilocarpine hydrochloride--
BADD_D01817Pramipexole--
BADD_D01818Pramipexole dihydrochloride--
BADD_D01835Pregabalin--
BADD_D01848Prochlorperazine--
BADD_D01858Propagermanium--
BADD_D01860Propantheline--
BADD_D01864Propofol0.000982%
BADD_D01867Propranolol--
BADD_D01868Propranolol hydrochloride--
BADD_D01909Ramipril0.000093%
BADD_D01916Rasagiline mesylate--
BADD_D01923Remifentanil hydrochloride--
BADD_D01951Risperidone0.000121%
BADD_D01968Ropivacaine hydrochloride--
BADD_D01981Salmeterol--
BADD_D01982Salmeterol xinafoate--
BADD_D02002Selegiline--
BADD_D02010Sertraline0.000025%
BADD_D02011Sertraline hydrochloride--
BADD_D02015Sevoflurane0.000357%
BADD_D02060Sotalol--
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