Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Leukaemia
ADR ID BADD_A02505
ADR Hierarchy
01      Blood and lymphatic system disorders
01.10      Leukaemias
01.10.03      Leukaemias NEC
01.10.03.001      Leukaemia
16      Neoplasms benign, malignant and unspecified (incl cysts and polyps)
16.01      Leukaemias
16.01.03      Leukaemias NEC
16.01.03.001      Leukaemia
Description A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006) [MeSH]
MedDRA Code 10024288
MeSH ID D007938
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Leukaemia | Leukaemia NOS | Leukaemia of unspecified cell type | Leukaemia of unspecified cell type, subacute | Leukaemia unspecified | Leukemia | Leukemia NOS | Leukemia of unspecified cell type | Leukemia of unspecified cell type, other | Leukemia of unspecified cell type, subacute | Other leukaemia of unspecified cell type | Other leukemia | Other leukemia of unspecified cell type | Other leukemia of unspecified cell type without mention of remission | Other specified leukaemia | Other specified leukaemias | Other specified leukemia | Other specified leukemia without mention of remission | Subacute leukaemia NOS | Subacute leukemia of unspecified cell type without mention of remission | Unspecified leukaemia | Unspecified leukemia | Unspecified leukemia without mention of remission | Leukaemia secondary | Leukemia secondary | Leukemia secondary to oncology chemotherapy | Leukemid | Subacute leukemia | Leukaemia secondary to oncology chemotherapy | Subacute leukaemia of unspecified cell type without mention of remission | Unspecified leukaemia without mention of remission | Leukemia unspecified | Treatment related leukemia | Treatment related leukaemia | Leukemias | Leucocythaemia | Leucocythaemias | Leucocythemia | Leucocythemias
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00871Felbamate--
BADD_D00979Furosemide0.000014%
BADD_D01035Golimumab--
BADD_D01095Hydrogen iodide--
BADD_D01110Hydroxyurea0.000336%
BADD_D01119Ibrutinib0.000224%
BADD_D01127Idarubicin--
BADD_D01136Imatinib0.001455%
BADD_D01156Indomethacin--
BADD_D01253Lenalidomide0.010657%
BADD_D01254Lenvatinib0.000224%
BADD_D01257Letrozole0.000263%
BADD_D01260Leuprolide acetate0.002868%
BADD_D01285Levothyroxine0.000005%
BADD_D01322Losartan0.000010%
BADD_D01336Macitentan0.000542%
BADD_D01376Melphalan--
BADD_D01392Mercaptopurine--
BADD_D01418Methotrexate--
BADD_D01506Muromonab-cd3--
BADD_D01507Mycophenolate mofetil--
BADD_D01567Nilotinib0.000672%
BADD_D01601Olaparib0.000728%
BADD_D01647Oxymetholone--
BADD_D01709Penicillamine--
BADD_D01731Pentoxifylline--
BADD_D01773Pimecrolimus--
BADD_D01799Ponatinib0.000168%
BADD_D01804Posaconazole0.018913%
BADD_D01835Pregabalin0.000207%
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