Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Low cardiac output syndrome
ADR ID BADD_A02581
ADR Hierarchy
02      Cardiac disorders
02.05      Heart failures
02.05.01      Heart failures NEC
02.05.01.008      Low cardiac output syndrome
Description A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities. [MeSH]
MedDRA Code 10024899
MeSH ID D002303
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Low cardiac output syndrome | Cardiac Output, Low | Output, Low Cardiac | Low Cardiac Output | Low Cardiac Output Syndrome
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00511Clozapine0.001223%
BADD_D00697Dobutamine0.000085%
BADD_D01574Nitric oxide-
BADD_D01679Paroxetine--
BADD_D01680Paroxetine hydrochloride--
BADD_D01681Paroxetine hydrochloride hemihydrate--
BADD_D01683Paroxetine mesylate--
BADD_D01954Rivaroxaban0.000063%
BADD_D02018Sildenafil0.000161%
BADD_D02261Tranexamic acid0.003117%
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