Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Macular degeneration
ADR ID BADD_A02632
ADR Hierarchy
06      Eye disorders
06.09      Ocular structural change, deposit and degeneration NEC
06.09.03      Retinal structural change, deposit and degeneration
06.09.03.001      Macular degeneration
Description Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms. [MeSH]
MedDRA Code 10025409
MeSH ID D008268
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cystoid macular degeneration of retina | Degeneration macular | Degeneration of macula and posterior pole of retina | Macula lutea degeneration | Macular & posterior pole degeneration | Macular degeneration | Macular luteal degeneration | Retinal macula lutea degeneration | Disciform macular degeneration | Macular degeneration progression | Retinal angiomatous proliferation | Atrophy of macula | Macula thinning | Macular Degeneration | Degeneration, Macular | Degenerations, Macular | Macular Degenerations | Age-Related Maculopathies | Age Related Maculopathies | Macular Degeneration, Age-Related | Macular Dystrophy | Dystrophies, Macular | Dystrophy, Macular | Macular Dystrophies | Maculopathies, Age-Related | Maculopathies, Age Related | Maculopathy, Age-Related | Maculopathy, Age Related | Age-Related Macular Degeneration | Age Related Macular Degeneration | Age-Related Macular Degenerations | Degeneration, Age-Related Macular | Degenerations, Age-Related Macular | Macular Degenerations, Age-Related | Age-Related Maculopathy | Age Related Maculopathy
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01253Lenalidomide0.004461%
BADD_D01257Letrozole0.000263%
BADD_D01285Levothyroxine0.000007%
BADD_D01290Lifitegrast0.001202%
BADD_D01336Macitentan0.000505%
BADD_D01378Memantine--
BADD_D01379Memantine hydrochloride--
BADD_D01418Methotrexate--
BADD_D01496Montelukast--
BADD_D01567Nilotinib0.000414%
BADD_D01629Osimertinib0.000224%
BADD_D01653Paclitaxel0.000112%
BADD_D01654Palbociclib0.000280%
BADD_D01690Pegaptanib--
BADD_D01817Pramipexole--
BADD_D01818Pramipexole dihydrochloride--
BADD_D01831Prednisolone0.000087%
BADD_D01834Prednisone0.000027%
BADD_D01835Pregabalin0.000441%
BADD_D01954Rivaroxaban0.000253%
BADD_D01966Ropinirole--
BADD_D01970Rosiglitazone maleate--
BADD_D01978Ruxolitinib0.000371%
BADD_D02006Selexipag0.000082%
BADD_D02018Sildenafil0.000322%
BADD_D02047Sodium oxybate0.000268%
BADD_D02093Sulfasalazine0.000455%
BADD_D02105Tacrolimus0.001248%
BADD_D02106Tadalafil0.000625%
BADD_D02112Tamoxifen citrate--
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