Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Malaise
ADR ID BADD_A02640
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.003      Malaise
Description A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling. [CTCAE]
MedDRA Code 10025482
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Feeling sick | Feeling unwell | Felt generally ill | Felt ill | General malaise | Generally off-colour | Generally unwell | Ill feeling | Malaise | Malaise and fatigue | Sickness feeling | Stamina decreased | Unwell | Generally off-color | Post-exertional malaise | Physically unwell
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01300Lisinopril--
BADD_D01309Lomefloxacin--
BADD_D01310Lomefloxacin hydrochloride--
BADD_D01311Lomitapide0.001407%
BADD_D01313Lomustine0.000168%
BADD_D01317Loratadine0.000373%
BADD_D01318Lorazepam--
BADD_D01322Losartan0.000593%
BADD_D01323Losartan potassium--
BADD_D01325Lovastatin--
BADD_D01328Lubiprostone0.002301%
BADD_D01330Lurasidone0.010297%
BADD_D01336Macitentan0.047222%
BADD_D01342Magnesium hydroxide0.008806%
BADD_D01345Magnevist--
BADD_D01349Mannitol--
BADD_D01352Maraviroc0.000282%
BADD_D01353Mebendazole0.005248%
BADD_D01354Mebeverine--
BADD_D01359Mechlorethamine0.002731%
BADD_D01363Meclofenamate sodium--
BADD_D01364Medronic acid--
BADD_D01366Medroxyprogesterone acetate0.002165%
BADD_D01368Mefenamic acid--
BADD_D01369Mefloquine--
BADD_D01370Mefloquine hydrochloride--
BADD_D01371Megestrol--
BADD_D01372Megestrol acetate--
BADD_D01373Melatonin0.000628%
BADD_D01374Meloxicam0.000117%
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