Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Malaise
ADR ID BADD_A02640
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.01      Asthenic conditions
08.01.01.003      Malaise
Description A disorder characterized by a feeling of general discomfort or uneasiness, an out-of-sorts feeling. [CTCAE]
MedDRA Code 10025482
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Feeling sick | Feeling unwell | Felt generally ill | Felt ill | General malaise | Generally off-colour | Generally unwell | Ill feeling | Malaise | Malaise and fatigue | Sickness feeling | Stamina decreased | Unwell | Generally off-color | Post-exertional malaise | Physically unwell
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02287Trimethadione--
BADD_D02290Trimethoprim0.003779%
BADD_D02294Trimipramine--
BADD_D02295Trimipramine maleate--
BADD_D02297Triptorelin--
BADD_D02301Troglitazone--
BADD_D02303Tropicamide0.004804%
BADD_D02307Trovafloxacin--
BADD_D02308Trovafloxacin mesylate--
BADD_D02312Ulipristal0.000270%
BADD_D02314Umeclidinium0.000299%
BADD_D02319Urofollitropin--
BADD_D02321Ursodiol--
BADD_D02325Valdecoxib--
BADD_D02326Valganciclovir--
BADD_D02329Valproic acid--
BADD_D02330Valrubicin--
BADD_D02331Valsartan0.005375%
BADD_D02335Vardenafil--
BADD_D02336Vardenafil hydrochloride--
BADD_D02337Varenicline0.022504%
BADD_D02338Varenicline tartrate--
BADD_D02342Vedolizumab--
BADD_D02345Venetoclax--
BADD_D02346Venlafaxine0.002234%
BADD_D02348Verapamil0.000534%
BADD_D02351Vernakalant hydrochloride--
BADD_D02352Verteporfin--
BADD_D02355Vigabatrin0.007683%
BADD_D02358Vinblastine--
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