Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Microangiopathic haemolytic anaemia
ADR ID BADD_A02770
ADR Hierarchy
01      Blood and lymphatic system disorders
01.06      Haemolyses and related conditions
01.06.02      Anaemias haemolytic mechanical factor
01.06.02.002      Microangiopathic haemolytic anaemia
24      Vascular disorders
24.03      Vascular disorders NEC
24.03.02      Non-site specific vascular disorders NEC
24.03.02.019      Microangiopathic haemolytic anaemia
Description A condition of inadequate circulating red blood cells (ANEMIA) or insufficient HEMOGLOBIN due to premature destruction of red blood cells (ERYTHROCYTES). | Acquired anemia due to destruction of red blood cells by physical trauma such as FIBRIN strands in the blood vessels, artificial heart valve, AORTIC COARCTATION. I can also be associated with hematologic diseases such as DISSEMINATED INTRAVASCULAR COAGULATION; HEMOLYTIC-UREMIC SYNDROME; and THROMBOTIC THROMBOCYTOPENIC PURPURA. [MeSH]
MedDRA Code 10027527
MeSH ID D000743
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Anaemia haemolytic, angiopathic | Microangiopathic haemolytic anaemia | Anemia hemolytic, angiopathic | Microangiopathic hemolytic anemia | Anemia, Hemolytic | Hemolytic Anemia | Microangiopathic Hemolytic Anemia | Anemia, Hemolytic, Acquired | Hemolytic Anemia, Acquired | Acquired Hemolytic Anemia | Anemia, Acquired Hemolytic | Anemia, Microangiopathic | Microangiopathic Anemia
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00364Carboplatin0.000112%
BADD_D00367Carfilzomib0.000280%
BADD_D00474Cisplatin0.000112%
BADD_D00504Clopidogrel0.000043%
BADD_D00551Cyclosporine--
BADD_D00653Diclofenac0.000026%
BADD_D00800Erlotinib--
BADD_D00858Everolimus0.000336%
BADD_D01009Gemcitabine0.000224%
BADD_D01010Gemcitabine hydrochloride--
BADD_D01281Levonorgestrel0.000473%
BADD_D01478Mitomycin--
BADD_D01506Muromonab-cd3--
BADD_D01633Oxaliplatin0.000112%
BADD_D01643Oxybutynin--
BADD_D01834Prednisone0.000027%
BADD_D01858Propagermanium--
BADD_D01895Quinine0.006605%
BADD_D02100Sunitinib0.000280%
BADD_D02105Tacrolimus0.000743%
BADD_D02324Valacyclovir hydrochloride--
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