Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Muscle spasms
ADR ID BADD_A02889
ADR Hierarchy
15      Musculoskeletal and connective tissue disorders
15.05      Muscle disorders
15.05.03      Muscle related signs and symptoms NEC
15.05.03.004      Muscle spasms
Description A sustained and usually painful contraction of muscle fibers. This may occur as an isolated phenomenon or as a manifestation of an underlying disease process (e.g., UREMIA; HYPOTHYROIDISM; MOTOR NEURON DISEASE; etc.). (From Adams et al., Principles of Neurology, 6th ed, p1398) [MeSH]
MedDRA Code 10028334
MeSH ID D009120; D013035; D013746
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Cramp | Cramp in hand | Cramp in legs thighs | Cramp legs | Cramp muscle | Cramp of limb | Cramps | Cramps calf | Cramps in legs | Cramps in the calves | Cramps leg | Cramps legs | Cramps of lower body | Cramps of lower extremities | Foot cramps | Generalized spasm | Leg cramps | Muscle cramp | Muscle cramps | Muscle cramps aggravated | Muscle spasm | Muscle spasms | Muscular spasm | Neck cramps | Night cramps | Nocturnal leg muscle cramps | Spasm generalised | Spasm generalized | Spasm muscle | Spasm of muscle | Spasms | Tetanic spasm generalized | Cervical spasm | Finger cramps | Systremma | Spasmophilia | Charley horse | Back muscle spasms | Generalised spasm | Tetanic spasm generalised | Cramps of upper extremities | Cramps of extremities | Toe cramps | Leg spasm | Muscle Cramp | Cramp, Muscle | Cramps, Muscle | Muscle Cramps | Muscular Cramp | Cramp, Muscular | Cramps, Muscular | Muscular Cramps | Limb Cramp | Cramp, Limb | Cramps, Limb | Limb Cramps
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01275Levofloxacin0.001957%
BADD_D01281Levonorgestrel--
BADD_D01282Levorphanol-
BADD_D01285Levothyroxine0.000561%
BADD_D01295Linezolid--
BADD_D01300Lisinopril--
BADD_D01303Lithium carbonate--
BADD_D01309Lomefloxacin--
BADD_D01310Lomefloxacin hydrochloride--
BADD_D01311Lomitapide0.000548%
BADD_D01318Lorazepam--
BADD_D01319Lorcaserin hydrochloride--
BADD_D01320Lorcaserin hydrochloride hemihydrate--
BADD_D01322Losartan--
BADD_D01323Losartan potassium--
BADD_D01325Lovastatin--
BADD_D01326Loxapine--
BADD_D01327Loxapine succinate--
BADD_D01328Lubiprostone--
BADD_D01330Lurasidone--
BADD_D01365Medroxyprogesterone--
BADD_D01366Medroxyprogesterone acetate--
BADD_D01369Mefloquine--
BADD_D01370Mefloquine hydrochloride--
BADD_D01373Melatonin0.000744%
BADD_D01374Meloxicam--
BADD_D01375Meloxicam sodium--
BADD_D01381Mepact--
BADD_D01384Meperidine--
BADD_D01389Mepolizumab--
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