Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Myocardial rupture
ADR ID BADD_A02938
ADR Hierarchy
02      Cardiac disorders
02.04      Myocardial disorders
02.04.02      Myocardial disorders NEC
02.04.02.002      Myocardial rupture
12      Injury, poisoning and procedural complications
12.01      Injuries NEC
12.01.11      Cardiovascular injuries
12.01.11.002      Myocardial rupture
Description Disease-related laceration or tearing of tissues of the heart, including the free-wall MYOCARDIUM; HEART SEPTUM; PAPILLARY MUSCLES; CHORDAE TENDINEAE; and any of the HEART VALVES. Pathological rupture usually results from myocardial infarction (HEART RUPTURE, POST-INFARCTION). [MeSH]
MedDRA Code 10028604
MeSH ID D006341
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cardiac rupture | Myocardial rupture | Myocardial rupture (post infarct) | Heart Rupture | Heart Ruptures | Cardiac Rupture | Cardiac Ruptures | Ventricular Free Wall Rupture | Free Wall Rupture, Heart | Cardiac Free Wall Rupture
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00260Betamethasone--
BADD_D00504Clopidogrel0.000021%
BADD_D00532Cortisone--
BADD_D00533Cortisone acetate--
BADD_D00623Dexamethasone--
BADD_D00624Dexamethasone phosphate--
BADD_D00625Dexamethasone sodium phosphate--
BADD_D01086Hydrocortisone--
BADD_D01091Hydrocortisone sodium succinate--
BADD_D01433Methylprednisolone--
BADD_D01434Methylprednisolone acetate--
BADD_D01435Methylprednisolone hemisuccinate--
BADD_D01436Methylprednisolone sodium succinate--
BADD_D01831Prednisolone--
BADD_D01832Prednisolone acetate--
BADD_D01834Prednisone--
BADD_D01929Reteplase--
BADD_D01961Rofecoxib--
BADD_D02070Streptokinase--
BADD_D02152Tenecteplase--
BADD_D02271Triamcinolone--
BADD_D02272Triamcinolone acetonide--
BADD_D02273Triamcinolone diacetate--
BADD_D02274Triamcinolone hexacetonide--
BADD_D02375Water--
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