| Pharmaceutical Information |
| Drug Name |
Tenecteplase |
| Drug ID |
BADD_D02152 |
| Description |
Tenecteplase is a tissue plasminogen activator (tPA) developed from modifications of natural human tPA complementary DNA (cDNA). It is a 527 amino acid with a substitution of threonine 103 with asparagine and substitution of asparagine 117 with glutamine within the kringle 1 domain, and a tetra-alanine substitution at amino acids 296-299 in the protease domain. |
| Indications and Usage |
For treatment of myocardial infarction and lysis of intracoronary emboli |
| Marketing Status |
approved |
| ATC Code |
B01AD11 |
| DrugBank ID |
DB00031
|
| KEGG ID |
D06070
|
| MeSH ID |
D000077785
|
| PubChem ID |
Not Available
|
| TTD Drug ID |
D0FX8A
|
| NDC Product Code |
50242-120 |
| UNII |
WGD229O42W
|
| Synonyms |
Tenecteplase | Metalyse | TNKase |
|
| Chemical Information |
| Molecular Formula |
Not Available |
| CAS Registry Number |
191588-94-0 |
| SMILES |
Not Available |
| Chemical Structure |
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| ADRs Induced by Drug |
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