Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Nystagmus
ADR ID BADD_A03102
ADR Hierarchy
06      Eye disorders
06.05      Ocular neuromuscular disorders
06.05.02      Ocular nerve and muscle disorders
06.05.02.006      Nystagmus
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.02      Coordination and balance disturbances
17.02.02.006      Nystagmus
Description A disorder characterized by involuntary movements of the eyeballs. [CTCAE] Involuntary movements of the eye that are divided into two types, jerk and pendular. Jerk nystagmus has a slow phase in one direction followed by a corrective fast phase in the opposite direction, and is usually caused by central or peripheral vestibular dysfunction. Pendular nystagmus features oscillations that are of equal velocity in both directions and this condition is often associated with visual loss early in life. (Adams et al., Principles of Neurology, 6th ed, p272) [MeSH]
MedDRA Code 10029864
MeSH ID D009759; D013036
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Dissociated nystagmus | Latent nystagmus | Nystagmus | Nystagmus and other irregular eye movements | Nystagmus associated with disorders of the vestibular system | Nystagmus NOS | Nystagmus, unspecified | Other forms of nystagmus | Visual deprivation nystagmus | Spasmus nutans | Gaze-evoked nystagmus | Rotational nystagmus | Nystagmus, Pathologic | Pathologic Nystagmus | Non-Fatigable Positional Nystagmus | Non Fatigable Positional Nystagmus | Nystagmus, Non-Fatigable Positional | Positional Nystagmus, Non-Fatigable | Permanent Nystagmus | Nystagmus, Permanent | Rebound Nystagmus | Nystagmus, Rebound | Retraction Nystagmus | Nystagmus, Retraction | Rotary Nystagmus | Nystagmus, Rotary | Rotational Nystagmus | Nystagmus, Rotational | See-Saw Nystagmus | Nystagmus, See-Saw | See Saw Nystagmus | Spontaneous Ocular Nystagmus | Nystagmus, Spontaneous Ocular | Ocular Nystagmus, Spontaneous | Symptomatic Nystagmus | Nystagmus, Symptomatic | Temporary Nystagmus | Nystagmus, Temporary | Unidirectional Nystagmus | Nystagmus, Unidirectional | Vertical Nystagmus | Nystagmus, Vertical | Conjugate Nystagmus | Nystagmus, Conjugate | Convergence Nystagmus | Nystagmus, Convergence | Dissociated Nystagmus | Nystagmus, Dissociated | Fatigable Positional Nystagmus | Nystagmus, Fatigable Positional | Horizontal Nystagmus | Nystagmus, Horizontal | Jerk Nystagmus | Nystagmus, Jerk | Multidirectional Nystagmus | Nystagmus, Multidirectional | Pendular Nystagmus | Nystagmus, Pendular | Periodic Alternating Nystagmus | Nystagmus, Periodic Alternating
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00039Acyclovir0.000178%
BADD_D00077Almotriptan--
BADD_D00078Almotriptan malate--
BADD_D00085Alprazolam0.000029%
BADD_D00209Baclofen0.000139%
BADD_D00269Bexarotene--
BADD_D00297Brivaracetam--
BADD_D00312Bupropion0.000138%
BADD_D00356Carbamazepine0.002418%
BADD_D00471Ciprofloxacin--
BADD_D00472Ciprofloxacin hydrochloride--
BADD_D00474Cisplatin0.000112%
BADD_D00475Citalopram--
BADD_D00476Citalopram hydrobromide--
BADD_D00488Clobazam--
BADD_D00499Clomipramine--
BADD_D00500Clomipramine hydrochloride--
BADD_D00501Clonazepam--
BADD_D00511Clozapine--
BADD_D00574Dalfampridine0.000538%
BADD_D00595Deferiprone--
BADD_D00603Delavirdine--
BADD_D00604Delavirdine mesylate--
BADD_D00648Diazepam0.000705%
BADD_D00686Diphenhydramine0.000940%
BADD_D00696Divalproex sodium--
BADD_D00706Donepezil--
BADD_D00707Donepezil hydrochloride--
BADD_D00723Doxorubicin--
BADD_D00734Duloxetine0.000053%
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ADReCS-Target
ADR Term Drug Name Target