Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Orthostatic hypotension
ADR ID BADD_A03212
ADR Hierarchy
17      Nervous system disorders
17.05      Neuromuscular disorders
17.05.01      Autonomic nervous system disorders
17.05.01.020      Orthostatic hypotension
24      Vascular disorders
24.06      Decreased and nonspecific blood pressure disorders and shock
24.06.03      Vascular hypotensive disorders
24.06.03.004      Orthostatic hypotension
Description A significant drop in BLOOD PRESSURE after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm Hg decrease in systolic pressure or a 10-mm Hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include DIZZINESS, blurred vision, and SYNCOPE. [MeSH]
MedDRA Code 10031127
MeSH ID D007024
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Hypotension orthostatic | Hypotension orthostatic asymptomatic | Hypotension orthostatic symptomatic | Hypotension postural | Orthostatic hypotension | Postural hypotension | Hypotension postural aggravated | Postural blood pressure drop | Hypotension, Orthostatic | Hypotension, Postural | Postural Hypotension | Orthostatic Hypotension
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01740Perindopril erbumine--
BADD_D01743Perphenazine--
BADD_D01750Phenelzine0.000094%
BADD_D01751Phenelzine sulfate--
BADD_D01754Phenoxybenzamine--
BADD_D01755Phenoxybenzamine hydrochloride--
BADD_D01758Phentolamine--
BADD_D01759Phentolamine mesylate--
BADD_D01762Phenylephrine--
BADD_D01765Phenytoin--
BADD_D01774Pimozide--
BADD_D01776Pindolol--
BADD_D01788Plerixafor--
BADD_D01789Plerixafor octahydrochloride--
BADD_D01797Polythiazide--
BADD_D01803Porfimer sodium--
BADD_D01804Posaconazole--
BADD_D01817Pramipexole0.000957%
BADD_D01818Pramipexole dihydrochloride--
BADD_D01827Prazosin--
BADD_D01835Pregabalin--
BADD_D01856Propafenone--
BADD_D01867Propranolol0.000080%
BADD_D01872Protriptyline--
BADD_D01873Protriptyline hydrochloride--
BADD_D01888Quetiapine0.000561%
BADD_D01889Quetiapine fumarate--
BADD_D01890Quinapril--
BADD_D01891Quinapril hydrochloride--
BADD_D01892Quinaprilat--
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ADReCS-Target
ADR Term Drug Name Target