Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Papilloedema
ADR ID BADD_A03285
ADR Hierarchy
06      Eye disorders
06.09      Ocular structural change, deposit and degeneration NEC
06.09.02      Optic disc abnormalities NEC
06.09.02.002      Papilloedema
17      Nervous system disorders
17.07      Increased intracranial pressure and hydrocephalus
17.07.02      Increased intracranial pressure disorders
17.07.02.004      Papilloedema
24      Vascular disorders
24.03      Vascular disorders NEC
24.03.07      Ocular vascular disorders NEC
24.03.07.001      Papilloedema
Description Swelling of the OPTIC DISK, usually in association with increased intracranial pressure, characterized by hyperemia, blurring of the disk margins, microhemorrhages, blind spot enlargement, and engorgement of retinal veins. Chronic papilledema may cause OPTIC ATROPHY and visual loss. (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p175) [MeSH]
MedDRA Code 10033712
MeSH ID D010211
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Disc congestion in ocular fundus | Disc oedema in ocular fundus | Disc redness in ocular fundus | Optic disc engorgement | Optic disc opacity | Optic nerve congestion | Optic nerve edema | Optic nerve oedema | Papilledema | Papilledema associated with decreased ocular pressure | Papilledema associated with increased intracranial pressure | Papilledema associated with retinal disorder | Papilledema, unspecified | Papilloedema | Disc edema in ocular fundus | Papilloedema associated with decreased ocular pressure | Papilloedema associated with increased intracranial pressure | Papilloedema associated with retinal disorder | Papilloedema, unspecified | Optic Disk Edema | Edema, Optic Disk | Edemas, Optic Disk | Optic Nerve Papillitis | Papillitis, Optic Nerve | Papillitis, Optic | Optic Papillitis | Papillitis | Choked Disk | Choked Disks | Disk, Choked | Disks, Choked | Optic Papilla Edema | Edema, Optic Papilla | Papilledema Associated with Increased Intracranial Pressure | Increased Intracranial Pressure-Associated Papilledema | Increased Intracranial Pressure Associated Papilledema | Edema of the optic disc | Retinal Edema | Edema, Retinal | Edemas, Retinal | Retinal Edemas | Decreased Intraocular Pressure-Associated Papilledema | Decreased Intraocular Pressure Associated Papilledema | Papilledema Associated with Decreased Intraocular Pressure
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00036Acitretin--
BADD_D00042Adapalene--
BADD_D00108Aminohippurate sodium--
BADD_D00115Amiodarone0.000202%
BADD_D00259Betaine0.004312%
BADD_D00260Betamethasone--
BADD_D00283Boceprevir--
BADD_D00284Bortezomib0.000112%
BADD_D00312Bupropion0.000083%
BADD_D00364Carboplatin0.000504%
BADD_D00374Carvedilol0.000021%
BADD_D00410Celecoxib0.000075%
BADD_D00474Cisplatin--
BADD_D00531Corticotropin--
BADD_D00532Cortisone--
BADD_D00533Cortisone acetate--
BADD_D00534Cosyntropin--
BADD_D00535Crizotinib0.000168%
BADD_D00551Cyclosporine0.000221%
BADD_D00556Cysteamine--
BADD_D00589Dasatinib0.000280%
BADD_D00595Deferiprone--
BADD_D00623Dexamethasone0.000218%
BADD_D00624Dexamethasone phosphate--
BADD_D00625Dexamethasone sodium phosphate--
BADD_D00643Diamminedichloroplatinum--
BADD_D00647Diatrizoic acid--
BADD_D00649Diazoxide--
BADD_D00736Dutasteride0.000797%
BADD_D00809Escitalopram0.000047%
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