Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Peyronie's disease
ADR ID BADD_A03400
ADR Hierarchy
21      Reproductive system and breast disorders
21.12      Penile and scrotal disorders (excl infections and inflammations)
21.12.01      Penile disorders NEC (excl erection and ejaculation)
21.12.01.002      Peyronie's disease
Description A condition characterized by hardening of the PENIS due to the formation of fibrous plaques on the dorsolateral aspect of the PENIS, usually involving the membrane (tunica albuginea) surrounding the erectile tissue (corpus cavernosum penis). This may eventually cause a painful deformity of the shaft or constriction of the urethra, or both. [MeSH]
MedDRA Code 10034765
MeSH ID D010411
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Peyronie's disease | Peyronies disease | Indurated penis plastica | Fibrous cavernitis | Penile induration | Fibrosis of the corpora cavernosa | Penile Induration | Penile Fibromatosis | Fibromatosis, Penile | Peyronie's Disease | Peyronies Disease | Plastic Induration of the Penis | Cavernitis, Fibrous | Cavernitides, Fibrous | Fibrous Cavernitides | Fibrous Cavernitis | Peyronie Disease
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D000064r,6r-dorzolamide--
BADD_D00019Acebutolol--
BADD_D00020Acebutolol hydrochloride--
BADD_D00086Alprostadil--
BADD_D00178Atenolol--
BADD_D00263Betaxolol--
BADD_D00277Bisoprolol--
BADD_D00278Bisoprolol fumarate--
BADD_D00374Carvedilol0.000041%
BADD_D00898Finasteride0.002359%
BADD_D01081Hydralazine0.000068%
BADD_D01236Labetalol--
BADD_D01237Labetalol hydrochloride--
BADD_D01439Methysergide--
BADD_D01445Metoprolol--
BADD_D01446Metoprolol succinate--
BADD_D01447Metoprolol tartrate--
BADD_D01512Nadolol--
BADD_D01706Penbutolol--
BADD_D01707Penbutolol sulfate--
BADD_D01765Phenytoin--
BADD_D01766Phenytoin sodium--
BADD_D01840Primidone0.000685%
BADD_D01867Propranolol--
BADD_D01868Propranolol hydrochloride--
BADD_D01966Ropinirole--
BADD_D02018Sildenafil0.000161%
BADD_D02053Sofosbuvir0.000960%
BADD_D02060Sotalol--
BADD_D02219Timolol0.000150%
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