Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Pleural effusion
ADR ID BADD_A03461
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.05      Pleural disorders
22.05.02      Pneumothorax and pleural effusions NEC
22.05.02.002      Pleural effusion
Description A disorder characterized by an increase in amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough and marked chest discomfort. [CTCAE] Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself. [MeSH]
MedDRA Code 10035598
MeSH ID D010996
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Effusion pleural | Intrapleural fluid retention of | Other specified forms of pleural effusion, except tuberculous | Pleural effusion | Unspecified pleural effusion | Pleural fluid exudate | Pulmonary effusion | Pleural effusion recurrent | Trapped lung | Bilateral pleural effusion | Unilateral pleural effusion | Pleural Effusion | Effusion, Pleural | Effusions, Pleural | Pleural Effusions
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02524Ivosidenib0.000302%
BADD_D02528Asciminib0.000280%
BADD_D02531Avapritinib0.000112%
BADD_D02539Calcium0.000391%
BADD_D02540Capmatinib0.000414%
BADD_D02545Dacomitinib0.000112%
BADD_D02553Entrectinib0.000224%
BADD_D02585Pralsetinib0.000112%
BADD_D02586Radium ra-223 dichloride-
BADD_D02591Ripretinib0.000168%
BADD_D02593Selpercatinib0.000112%
BADD_D02596Sotorasib0.000224%
BADD_D02599Tepotinib0.000112%
BADD_D02603Tucatinib0.000112%
BADD_D02609Zanubrutinib0.000224%
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