Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Pleural effusion
ADR ID BADD_A03461
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.05      Pleural disorders
22.05.02      Pneumothorax and pleural effusions NEC
22.05.02.002      Pleural effusion
Description A disorder characterized by an increase in amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough and marked chest discomfort. [CTCAE] Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself. [MeSH]
MedDRA Code 10035598
MeSH ID D010996
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Effusion pleural | Intrapleural fluid retention of | Other specified forms of pleural effusion, except tuberculous | Pleural effusion | Unspecified pleural effusion | Pleural fluid exudate | Pulmonary effusion | Pleural effusion recurrent | Trapped lung | Bilateral pleural effusion | Unilateral pleural effusion | Pleural Effusion | Effusion, Pleural | Effusions, Pleural | Pleural Effusions
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00511Clozapine--
BADD_D00535Crizotinib0.006078%
BADD_D00549Cyclophosphamide--
BADD_D00560Cytarabine0.001589%
BADD_D00563Dabigatran0.007511%
BADD_D00564Dabigatran etexilate--
BADD_D00571Dactinomycin0.000112%
BADD_D00577Dantrolene sodium--
BADD_D00580Dapsone0.001467%
BADD_D00581Daptomycin0.000170%
BADD_D00589Dasatinib0.070593%
BADD_D00593Decitabine0.000560%
BADD_D00594Deferasirox--
BADD_D00623Dexamethasone0.001744%
BADD_D00629Dexmedetomidine--
BADD_D00630Dexmedetomidine hydrochloride--
BADD_D00668Digoxin0.000211%
BADD_D00669Digoxin immune fab (ovine)--
BADD_D00699Docetaxel--
BADD_D00704Dolutegravir sodium0.000423%
BADD_D00723Doxorubicin0.002462%
BADD_D00730Dronedarone0.000490%
BADD_D00766Emtricitabine0.002800%
BADD_D00768Enalaprilat0.004052%
BADD_D00773Entacapone0.004115%
BADD_D00774Entecavir0.004903%
BADD_D00775Enzalutamide--
BADD_D00784Epirubicin0.000168%
BADD_D00788Epoprostenol0.000576%
BADD_D00798Eribulin0.001444%
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