Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Pleural effusion
ADR ID BADD_A03461
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.05      Pleural disorders
22.05.02      Pneumothorax and pleural effusions NEC
22.05.02.002      Pleural effusion
Description A disorder characterized by an increase in amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough and marked chest discomfort. [CTCAE] Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself. [MeSH]
MedDRA Code 10035598
MeSH ID D010996
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Effusion pleural | Intrapleural fluid retention of | Other specified forms of pleural effusion, except tuberculous | Pleural effusion | Unspecified pleural effusion | Pleural fluid exudate | Pulmonary effusion | Pleural effusion recurrent | Trapped lung | Bilateral pleural effusion | Unilateral pleural effusion | Pleural Effusion | Effusion, Pleural | Effusions, Pleural | Pleural Effusions
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00802Ertapenem--
BADD_D00803Ertapenem sodium--
BADD_D00813Esmolol--
BADD_D00843Ethanolamine oleate--
BADD_D00858Everolimus0.010442%
BADD_D00861Exemestane0.003137%
BADD_D00871Felbamate--
BADD_D00873Fenofibrate0.000059%
BADD_D00879Fentanyl--
BADD_D00880Fentanyl citrate--
BADD_D00914Fludarabine0.000224%
BADD_D00931Fluorouracil0.000827%
BADD_D00932Fluoxetine0.000167%
BADD_D00946Fluticasone furoate--
BADD_D00978Fulvestrant0.002736%
BADD_D00979Furosemide0.000208%
BADD_D00998Gallium cation--
BADD_D01000Gallium nitrate--
BADD_D01003Ganciclovir--
BADD_D01008Gefitinib0.001063%
BADD_D01009Gemcitabine0.001399%
BADD_D01010Gemcitabine hydrochloride--
BADD_D01020Glatiramer--
BADD_D01021Glatiramer acetate--
BADD_D01024Glipizide0.000026%
BADD_D01062Hepatitis b immune globulin (human)--
BADD_D01081Hydralazine0.000239%
BADD_D01083Hydrochlorothiazide0.000025%
BADD_D01099Hydroxocobalamin--
BADD_D01110Hydroxyurea0.000504%
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