Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Pleural effusion
ADR ID BADD_A03461
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.05      Pleural disorders
22.05.02      Pneumothorax and pleural effusions NEC
22.05.02.002      Pleural effusion
Description A disorder characterized by an increase in amounts of fluid within the pleural cavity. Symptoms include shortness of breath, cough and marked chest discomfort. [CTCAE] Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself. [MeSH]
MedDRA Code 10035598
MeSH ID D010996
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Effusion pleural | Intrapleural fluid retention of | Other specified forms of pleural effusion, except tuberculous | Pleural effusion | Unspecified pleural effusion | Pleural fluid exudate | Pulmonary effusion | Pleural effusion recurrent | Trapped lung | Bilateral pleural effusion | Unilateral pleural effusion | Pleural Effusion | Effusion, Pleural | Effusions, Pleural | Pleural Effusions
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01601Olaparib0.000951%
BADD_D01617Ondansetron0.000021%
BADD_D01620Oprelvekin--
BADD_D01629Osimertinib0.005294%
BADD_D01633Oxaliplatin0.000839%
BADD_D01653Paclitaxel0.002071%
BADD_D01654Palbociclib0.010409%
BADD_D01661Pamidronate disodium--
BADD_D01662Pamidronic acid0.000126%
BADD_D01679Paroxetine0.000064%
BADD_D01687Pazopanib0.003033%
BADD_D01690Pegaptanib--
BADD_D01691Pegaptanib sodium--
BADD_D01700Pembrolizumab--
BADD_D01701Pemetrexed0.000616%
BADD_D01735Pergolide--
BADD_D01736Pergolide mesylate--
BADD_D01744Pertuzumab--
BADD_D01756Phentermine0.000164%
BADD_D01783Pirfenidone--
BADD_D01786Pixantrone--
BADD_D01799Ponatinib0.001198%
BADD_D01800Ponatinib hydrochloride--
BADD_D01802Porfimer--
BADD_D01803Porfimer sodium--
BADD_D01804Posaconazole0.009456%
BADD_D01814Pralatrexate0.000112%
BADD_D01817Pramipexole0.000319%
BADD_D01822Prasugrel0.000384%
BADD_D01831Prednisolone0.000559%
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