Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Portal hypertension
ADR ID BADD_A03513
ADR Hierarchy
09      Hepatobiliary disorders
09.01      Hepatic and hepatobiliary disorders
09.01.06      Hepatic vascular disorders
09.01.06.006      Portal hypertension
24      Vascular disorders
24.08      Vascular hypertensive disorders
24.08.06      Portal hypertensions
24.08.06.001      Portal hypertension
Description A disorder characterized by an increase in blood pressure in the portal venous system. [CTCAE] Abnormal increase of resistance to blood flow within the hepatic PORTAL SYSTEM, frequently seen in LIVER CIRRHOSIS and conditions with obstruction of the PORTAL VEIN. | Liver cirrhosis with intrahepatic portal obstruction, HYPERTENSION, and patent UMBILICAL VEINS. [MeSH]
MedDRA Code 10036200
MeSH ID D006975
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE)
Synonym
Hypertension portal | Portal hypertension | Cruveilhier-Baumgarten syndrome | Hypertension, Portal | Hypertensions, Portal | Portal Hypertension | Portal Hypertensions | Cruveilhier-Baumgarten Syndrome | Cruveilhier Baumgarten Syndrome | Syndrome, Cruveilhier-Baumgarten
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00023Acetaminophen--
BADD_D00046Ado-trastuzumab emtansine--
BADD_D00195Azathioprine0.003290%
BADD_D00285Bosentan0.000241%
BADD_D00349Capecitabine0.000224%
BADD_D00412Cephalexin--
BADD_D00474Cisplatin0.000168%
BADD_D00504Clopidogrel0.000021%
BADD_D00551Cyclosporine0.000166%
BADD_D00589Dasatinib0.000112%
BADD_D00661Didanosine--
BADD_D00695Disulfiram0.003777%
BADD_D00788Epoprostenol0.000082%
BADD_D00858Everolimus0.000535%
BADD_D00931Fluorouracil0.000643%
BADD_D01110Hydroxyurea0.000112%
BADD_D01119Ibrutinib0.000112%
BADD_D01220Ivacaftor-
BADD_D01254Lenvatinib0.000112%
BADD_D01336Macitentan0.000120%
BADD_D01392Mercaptopurine0.007286%
BADD_D01592Obeticholic acid0.006776%
BADD_D01633Oxaliplatin0.001892%
BADD_D01653Paclitaxel0.000112%
BADD_D01826Praziquantel0.002536%
BADD_D01905Raltegravir0.001648%
BADD_D01933Ribavirin0.019779%
BADD_D01938Rifaximin0.000322%
BADD_D01951Risperidone0.000242%
BADD_D01978Ruxolitinib0.000343%
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