Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Presyncope
ADR ID BADD_A03545
ADR Hierarchy
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.05      Neurological signs and symptoms NEC
17.02.05.009      Presyncope
24      Vascular disorders
24.06      Decreased and nonspecific blood pressure disorders and shock
24.06.02      Circulatory collapse and shock
24.06.02.010      Presyncope
02      Cardiac disorders
02.11      Cardiac disorders, signs and symptoms NEC
02.11.04      Cardiac signs and symptoms NEC
02.11.04.013      Presyncope
Description A disorder characterized by an episode of lightheadedness and dizziness which may precede an episode of syncope. [CTCAE] A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9) [MeSH]
MedDRA Code 10036653
MeSH ID D013575
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Lipothymia | Pre-syncope | Presyncope | Vagal reaction | Vaso vagal attack | Vasovagal attack | Vasovagal reaction | Vasovagal symptoms | Orthostatic presyncope | Near fainting | Near syncope | Hypotensive presyncope | Syncope | Syncopes | Fainting | Presyncopes | Syncopal Episode | Episode, Syncopal | Syncopal Episodes | Syncopal Vertigo | Vertigo, Syncopal | Vertigos, Syncopal | Syncope, Cardiogenic | Cardiogenic Syncope | Cardiogenic Syncopes | Syncopes, Cardiogenic | Syncope, Carotid Sinus | Carotid Sinus Syncope | Carotid Sinus Syncopes | Syncopes, Carotid Sinus | Syncope, Convulsive | Convulsive Syncope | Convulsive Syncopes | Syncopes, Convulsive | Syncope, Deglutitional | Deglutitional Syncope | Deglutitional Syncopes | Syncopes, Deglutitional | Syncope, Effort | Effort Syncope | Effort Syncopes | Syncopes, Effort | Syncope, Hyperventilation | Hyperventilation Syncope | Hyperventilation Syncopes | Syncopes, Hyperventilation | Syncope, Micturition | Micturition Syncope | Micturition Syncopes | Syncopes, Micturition | Syncope, Postural | Postural Syncope | Postural Syncopes | Syncopes, Postural | Syncope, Situational | Situational Syncope | Situational Syncopes | Syncopes, Situational | Syncope, Stokes-Adams | Stokes-Adams Syncope | Stokes-Adams Syncopes | Syncope, Stokes Adams | Syncopes, Stokes-Adams | Syncope, Tussive | Syncopes, Tussive | Tussive Syncope | Tussive Syncopes | Drop Attack | Attack, Drop | Drop Attacks
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02392Zoledronic acid0.007157%
BADD_D02393Zolmitriptan0.001354%
BADD_D02394Zolpidem0.000076%
BADD_D02412Octreotide--
BADD_D02436Atorvastatin--
BADD_D02441Rasagiline0.003572%
BADD_D02445Solifenacin0.000174%
BADD_D02464Fingolimod0.004002%
BADD_D02470Nintedanib--
BADD_D02473Sodium chloride0.000483%
BADD_D02487Baricitinib0.000530%
BADD_D02510Rucaparib0.000548%
BADD_D02537Cabotegravir0.000282%
BADD_D02539Calcium0.000861%
BADD_D02558Gadolinium cation (3+)-
BADD_D02579Oxymetazoline0.000480%
BADD_D02586Radium ra-223 dichloride-
BADD_D02603Tucatinib0.000112%
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