Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Pulmonary veno-occlusive disease
ADR ID BADD_A03654
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.06      Pulmonary vascular disorders
22.06.03      Vascular pulmonary disorders NEC
22.06.03.003      Pulmonary veno-occlusive disease
24      Vascular disorders
24.01      Embolism and thrombosis
24.01.06      Pulmonary embolism and thrombosis
24.01.06.008      Pulmonary veno-occlusive disease
Description Pathological process resulting in the fibrous obstruction of the small- and medium-sized PULMONARY VEINS and PULMONARY HYPERTENSION. Veno-occlusion can arise from fibrous proliferation of the VASCULAR INTIMA and VASCULAR MEDIA; THROMBOSIS; or a combination of both. [MeSH]
MedDRA Code 10037458
MeSH ID D011668
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Pulmonary veno-occlusive disease | Pulmonary Veno-Occlusive Disease | Diseases, Pulmonary Veno-Occlusive | Pulmonary Veno-Occlusive Diseases | Veno-Occlusive Diseases, Pulmonary | Veno-Occlusive Disease, Pulmonary | Veno Occlusive Disease, Pulmonary | Pulmonary Venoocclusive Disease | Pulmonary Venoocclusive Diseases | Venoocclusive Disease, Pulmonary | Venoocclusive Diseases, Pulmonary | Pulmonary Veno Occlusive Disease
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00100Ambrisentan0.000469%
BADD_D00285Bosentan0.000361%
BADD_D00318Busulfan0.000112%
BADD_D00549Cyclophosphamide--
BADD_D00551Cyclosporine0.000111%
BADD_D00788Epoprostenol0.000329%
BADD_D01135Iloprost0.000082%
BADD_D01336Macitentan0.000361%
BADD_D01478Mitomycin0.000336%
BADD_D02006Selexipag0.000263%
BADD_D02106Tadalafil0.000195%
BADD_D02268Treprostinil0.000535%
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