Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Pupillary reflex impaired
ADR ID BADD_A03664
ADR Hierarchy
06      Eye disorders
06.05      Ocular neuromuscular disorders
06.05.03      Pupil disorders
06.05.03.009      Pupillary reflex impaired
17      Nervous system disorders
17.02      Neurological disorders NEC
17.02.11      Pupillary signs
17.02.11.007      Pupillary reflex impaired
Description Conditions which affect the structure or function of the pupil of the eye, including disorders of innervation to the pupillary constrictor or dilator muscles, and disorders of pupillary reflexes. | Conditions in which the pupil does not react normally to dilation and constriction. Signs of pupillary abnormalities originate from the pupil's shape, position, and response to stimulation. [MeSH]
MedDRA Code 10037532
MeSH ID D011681
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Light reflex sluggish | Pupillary light reflex lost | Pupillary reaction slow | Pupillary reflex absent | Pupillary reflex impaired | Marcus Gunn pupil | Relative afferent pupillary defect | Efferent pupillary defect | Pupil Disorders | Pupil Disorder | Pupillary Disorders | Pupillary Disorder | Pupil Reaction Absent | Reaction Absent, Pupil | Reaction Absents, Pupil | Pupillary Sector Paralysis | Paralyses, Pupillary Sector | Paralysis, Pupillary Sector | Pupillary Sector Paralyses | Sector Paralyses, Pupillary | Sector Paralysis, Pupillary | Sector Pupil Palsy | Pupillary Sphincter Rupture | Pupillary Sphincter Ruptures | Rupture, Pupillary Sphincter | Ruptures, Pupillary Sphincter | Sphincter Rupture, Pupillary | Sphincter Ruptures, Pupillary | Wernicke Hemianopic Pupil | Hemianopic Pupil, Wernicke | Pupil, Wernicke Hemianopic | Wernicke's Hemianopic Pupil | Hemianopic Pupil, Wernicke's | Pupil, Wernicke's Hemianopic | Wernickes Hemianopic Pupil | Afferent Pupillary Defect | Afferent Pupillary Defects | Pupillary Defect, Afferent | Pupillary Defects, Afferent | Marcus-Gunn Pupil | Marcus Gunn Pupil | Pupil, Marcus-Gunn | Deformed Pupil | Deformed Pupils | Pupil, Deformed | Pupils, Deformed | Ectopic Pupil | Ectopic Pupils | Pupil, Ectopic | Pupils, Ectopic | Efferent Pupillary Defect | Efferent Pupillary Defects | Pupillary Defect, Efferent | Pupillary Defects, Efferent | Fixed Pupils | Fixed Pupil | Pupil, Fixed | Pupils, Fixed | Keyhole Pupil | Keyhole Pupils | Pupil, Keyhole | Pupils, Keyhole | Non-Syphilitic Argyll-Robertson Pupil | Argyll-Robertson Pupil, Non-Syphilitic | Non Syphilitic Argyll Robertson Pupil | Pupil, Non-Syphilitic Argyll-Robertson | Occluded Pupils | Occluded Pupil | Pupil, Occluded | Pupils, Occluded | Pupillary Occlusion | Occlusion, Pupillary | Occlusions, Pupillary | Pupillary Occlusions | Pupil Malformations | Malformation, Pupil | Malformations, Pupil | Pupil Malformation | Pupillary Anomaly | Anomalies, Pupillary | Anomaly, Pupillary | Pupillary Anomalies | Pupillary Functions, Abnormal | Abnormal Pupillary Function | Abnormal Pupillary Functions | Pupillary Function, Abnormal | Pupillary Paralysis | Paralyses, Pupillary | Paralysis, Pupillary | Pupillary Paralyses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00189Atropine0.000138%
BADD_D00209Baclofen0.000174%
BADD_D00312Bupropion0.000028%
BADD_D00356Carbamazepine0.000279%
BADD_D00399Ceftazidime0.000073%
BADD_D00511Clozapine0.002446%
BADD_D00686Diphenhydramine0.000336%
BADD_D00898Finasteride0.000045%
BADD_D01318Lorazepam0.000031%
BADD_D01405Methadone0.000265%
BADD_D01445Metoprolol0.000007%
BADD_D01470Minocycline0.000177%
BADD_D01498Morphine0.000557%
BADD_D01594Ocriplasmin--
BADD_D01599Olanzapine0.000316%
BADD_D01645Oxycodone0.000062%
BADD_D01690Pegaptanib--
BADD_D01765Phenytoin0.000287%
BADD_D01831Prednisolone0.000035%
BADD_D01848Prochlorperazine--
BADD_D01951Risperidone0.000182%
BADD_D02047Sodium oxybate0.000402%
BADD_D02105Tacrolimus0.000446%
BADD_D02106Tadalafil0.000195%
BADD_D02115Tapentadol0.000637%
BADD_D02346Venlafaxine--
BADD_D02415Ziprasidone0.000408%
BADD_D02464Fingolimod0.000772%
BADD_D02475Methylene blue0.000183%
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