Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Raynaud's phenomenon
ADR ID BADD_A03708
ADR Hierarchy
24      Vascular disorders
24.04      Arteriosclerosis, stenosis, vascular insufficiency and necrosis
24.04.03      Peripheral vasoconstriction, necrosis and vascular insufficiency
24.04.03.003      Raynaud's phenomenon
Description An idiopathic vascular disorder characterized by bilateral Raynaud phenomenon, the abrupt onset of digital paleness or CYANOSIS in response to cold exposure or stress. [MeSH]
MedDRA Code 10037912
MeSH ID D011928
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Raynaud like disorder | Raynaud's disease | Raynaud's disease aggravated | Raynaud's phenomenon | Raynaud's phenomenon aggravated | Raynaud's syndrome | Raynaud-like disorder | Raynaud-like phenomena | Raynauds | Raynauds phenomena of feet | Raynauds' phen | Raynaud Disease | Cold Fingers, Hereditary | Raynaud's Disease | Raynauds Disease | Raynaud Phenomenon
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00898Finasteride0.000099%
BADD_D01009Gemcitabine--
BADD_D01046Guanfacine0.002439%
BADD_D01083Hydrochlorothiazide0.000010%
BADD_D01136Imatinib0.000112%
BADD_D01137Imatinib mesylate--
BADD_D01139Imipramine--
BADD_D01166Interferon alfa-2a--
BADD_D01167Interferon alfa-2b--
BADD_D01236Labetalol0.000602%
BADD_D01257Letrozole0.000263%
BADD_D01281Levonorgestrel0.001655%
BADD_D01285Levothyroxine0.000005%
BADD_D01300Lisinopril0.000015%
BADD_D01336Macitentan0.000710%
BADD_D01418Methotrexate0.000500%
BADD_D01431Methylphenidate0.000185%
BADD_D01432Methylphenidate hydrochloride--
BADD_D01445Metoprolol--
BADD_D01447Metoprolol tartrate--
BADD_D01512Nadolol--
BADD_D01541Nebivolol--
BADD_D01542Nebivolol hydrochloride--
BADD_D01566Nifedipine0.000276%
BADD_D01567Nilotinib0.000638%
BADD_D01595Octreotide acetate--
BADD_D01653Paclitaxel0.000336%
BADD_D01798Pomalidomide0.001881%
BADD_D01799Ponatinib0.000437%
BADD_D01817Pramipexole--
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ADReCS-Target
ADR Term Drug Name Target